Results 141 to 150 of about 5,603,208 (256)
Advanced Science, EarlyView.Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang +4 more
wiley +1 more source
IN.PACTTM AdmiralTM drug-coated balloons in peripheral artery disease: current perspectives
, 2019 Sho Torii, Frank D Kolodgie, Renu Virmani, Aloke V Finn Cardiovascular Pathology, CVPath Institute, Inc., Gaithersburg, MD, USA Abstract: Endovascular therapy has evolved as a main treatment option especially in patients with short (<25 cm ...
Finn AV, Torii S, Virmani R, Kolodgie FD
core
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
Advanced Science, EarlyView.This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A
Advanced Science, EarlyView.THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu +15 more
wiley +1 more source
Prediction of Peripheral Artery Disease Prognosis Using Clinical and Inflammatory Biomarker Data [PDF]
Ben Li,1– 4,* Farah Shaikh,2,* Abdelrahman Zamzam,2 Ravel Raphael,2 Muzammil H Syed,2 Houssam K Younes,5 Rawand Abdin,6 Mohammad Qadura1– 3,7 1Department of Surgery, University of Toronto, Toronto, Ontario, Canada; 2Division of Vascular Surgery ...
Raphael R +7 more
core
Advanced Science, EarlyView.Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu +5 more
wiley +1 more source
Cardiovascular regulation and vascular structure in prehypertension and coronary heart disease [PDF]
, 2009 The aim of this thesis was to characterize vascular structure and different aspects of cardiovascular regulation in otherwise healthy subjects with slightly elevated blood pressure and compare to healthy subjects with normotension and also investigate ...
Myredal, Anna
core
Advanced Science, EarlyView.Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit +10 more
wiley +1 more source
Медицина в Кузбассе, 2018 Objective – to investigate the structure of non-surgical complications after operation, define its effect on in-hospital mortality in lower limb amputations in patients with peripheral artery disease. Materials.
Денис Николаевич Макаров +1 more
doaj