Results 51 to 60 of about 308,781 (312)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Stem Cell Therapies in Peripheral Vascular Diseases — Current Status

Journal of Interdisciplinary Medicine, 2017
Peripheral artery diseases include all arterial diseases with the exception of coronary and aortic involvement, more specifically diseases of the extracranial carotids, upper limb arteries, mesenteric and renal vessels, and last but not least, lower limb
Opincariu Diana, Mester András, Benedek Imre, Benedek István   +3 more
doaj   +1 more source

Prevalence of peripheral artery disease in young coronary artery disease patients [PDF]

Romanian Medical Journal
Background and objectives. Peripheral artery disease (PAD) and coronary artery disease (CAD) are progressive inflammatory conditions caused by arteriosclerosis, typically presenting after the age of 50. However, assessing peripheral vascular disease (PVD)
Medikonda Malla Reddy, N. Krishna Geetha, Kakumani Jagadeswar, I. Mariraj, K.I.S.N. Vaishnavi, Fahad Dadu, Gowri Shankar A.   +6 more
doaj   +1 more source

Factors determining acceptance of disease and its impact on satisfaction with life of patients with peripheral artery disease

Nursing Open, 2021
Aims and objectives Analysis of factors determining acceptance of disease and satisfaction with life in patients with peripheral artery disease. Background Peripheral artery disease is more common in older patients and is associated with increased ...
Renata Piotrkowska, Sylwia Terech‐Skóra, Wioletta Mędrzycka‐Dąbrowska, Piotr Jarzynkowski, Magdalena Król   +4 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Combining diabetic foot and retinopathy screening: A step in the right direction? – a feasibility study

SAGE Open Medicine, 2020
Objectives: Peripheral artery disease is a major cardiovascular disease affecting more than 200 million people globally and up to 4 times more frequent in the diabetic population.
Jane EA Lewis, Keith Morris, Thomas Powell, Rebecca L Thomas, David R Owens   +4 more
doaj   +1 more source

Lower extremity amputation in peripheral artery disease: improving patient outcomes [PDF]

, 2014
Aparna Swaminathan,1 Sreekanth Vemulapalli,1,2 Manesh R Patel,1,2 W Schuyler Jones1,2 1Department of Medicine, Duke University Medical Center, Durham, NC, USA; 2Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA Abstract:
Patel MR, Jones WS, Swaminathan A, Vemulapalli S   +3 more
core  

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Current insights into drug-coated balloons for peripheral arterial disease [PDF]

Introduction: Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis. It is often associated with coronary and/or cerebral vascular involvement, leading to a higher risk of cardiovascular and cerebrovascular events, among which ...
Virga V, Micari A, Roscitano G, Vadalà G, Di Bella G, Versace A, Vizzari G. Current insights into drug-coated balloons for peripheral arterial disease., Costa F   +7 more
core   +1 more source

Peripheral Artery Disease: A comprehensive updated review [PDF]

, 2022
Peripheral arterial disease is estimated to affect more than 200 million people worldwide. Although more than 50% of those affected are asymptomatic, it accounts for 3-4% of amputations and a crude five-year death rate of 82.4 deaths per 1000 patient ...
Olaseni, Bamgbose Michael, Charles, Agwuegbo Chibuike, Shamaki, Garba Rimamskep, Favour, Markson, Bob-Manuel, Tamunoinemi, Demilade, Soji-Ayoade   +5 more
core   +1 more source