Results 51 to 60 of about 5,603,208 (256)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Case Report: Multiple atherosclerotic plaques at its extreme in synchrony [version 3; peer review: 2 approved]

F1000Research
Peripheral artery (PAD) disease in association with renal artery stenosis is an important association which predicts the severity of the disease. An increase in the number of vessels affected by peripheral artery disease increases the chances of renal ...
Gajendra Agrawal, Satish Khadse, Kashish Khurana, Benumadhab Ghosh, Sourya Acharya, Anuj Chaturvedi, Saket Toshniwal, Isha Sahai, Sunil Kumar   +8 more
doaj   +1 more source

Prevalence of peripheral artery disease in young coronary artery disease patients [PDF]

Romanian Medical Journal
Background and objectives. Peripheral artery disease (PAD) and coronary artery disease (CAD) are progressive inflammatory conditions caused by arteriosclerosis, typically presenting after the age of 50. However, assessing peripheral vascular disease (PVD)
Medikonda Malla Reddy, N. Krishna Geetha, Kakumani Jagadeswar, I. Mariraj, K.I.S.N. Vaishnavi, Fahad Dadu, Gowri Shankar A.   +6 more
doaj   +1 more source

Combining diabetic foot and retinopathy screening: A step in the right direction? – a feasibility study

SAGE Open Medicine, 2020
Objectives: Peripheral artery disease is a major cardiovascular disease affecting more than 200 million people globally and up to 4 times more frequent in the diabetic population.
Jane EA Lewis, Keith Morris, Thomas Powell, Rebecca L Thomas, David R Owens   +4 more
doaj   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Peripheral Arterial Disease [PDF]

Clinical Journal of the American Society of Nephrology, 2007
Cardiovascular disease is a major source of morbidity and mortality for patients with chronic kidney disease (CKD). Peripheral arterial disease (PAD) is a strong predictor of coronary artery disease and a risk factor for mortality in the general population.
Stephanie S, DeLoach, Emile R, Mohler
openaire   +2 more sources

Peripheral artery disease in diabetes

Frontiers in Endocrinology
Peripheral artery disease in diabetes mellitus represents a distinct clinical entity characterized by diffuse distal arterial disease, medial calcification, microvascular dysfunction, neuropathy, and a pro-thromboinflammatory milieu.
Sheena Amin, Eri Fukaya, Anand Athavale
doaj   +1 more source

Factors determining acceptance of disease and its impact on satisfaction with life of patients with peripheral artery disease

Nursing Open, 2021
Aims and objectives Analysis of factors determining acceptance of disease and satisfaction with life in patients with peripheral artery disease. Background Peripheral artery disease is more common in older patients and is associated with increased ...
Renata Piotrkowska, Sylwia Terech‐Skóra, Wioletta Mędrzycka‐Dąbrowska, Piotr Jarzynkowski, Magdalena Król   +4 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source