Results 211 to 220 of about 1,101,865 (283)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Crystal Sensing and Neurogenic Inflammation in Gout: A Proposed Sensory Neuroimmune Framework for Flare Pain. [PDF]

J Pain Res
Dong X, Xu R, Liang J, Qiu Y, Tong Y.
europepmc   +1 more source

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen, Patrick C. Souverein, Eibert R. Heerdink, Elisabeth Y. Bijlsma, Lucianne Groenink   +4 more
wiley   +1 more source

Inflammatory Eye Disease and Immunosuppressive Therapy: A Rheumatologist's Perspective. [PDF]

Cureus
Aung T.
europepmc   +1 more source

Trans‐Patch Retrograde Re‐Entry During Hybrid Revascularization of an External Iliac Artery Chronic Total Occlusion: A Technical Note and Review of Re‐Entry Strategies

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Failure of true‐lumen re‐entry after subintimal wire passage is a well‐recognized limitation of endovascular treatment for external iliac artery (EIA) chronic total occlusions (CTO). We report a 73‐year‐old woman with severe limb ischemia and a prior failed endovascular attempt who underwent hybrid left common femoral artery (CFA ...
Bibhas Amatya, Dipankar Mukherjee
wiley   +1 more source

Bilateral Diffuse Anterior Scleritis With Ocular Hypertension Revealing Rheumatoid Arthritis. [PDF]

Cureus
Loubna M, Liqali F, Tidrarine S, Bouslous N, Omar MM.   +4 more
europepmc   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

Metabolic reprogramming of NK cells in chronic brucellar arthritis: role of the HIF-1α/mTOR axis. [PDF]

Front Immunol
Sheng G, Li W, Liu D, Ren X, Wei M, Yang Z, Tian W, Zhang F, Zhu Y, Zeng F, Zhao Z, Xu P, Tian H, Pang N, Li C, Zhang Z.   +15 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source