CLINICAL ASSESSMENT IN PSORIATIC ARTHRITIS
Due to the heterogenous clinical picture, with a possible combination in any individual patient of axial disease, peripheral arthritis, enthesitis and dactylitis, psoriatic arthritis (PsA) is difficult to assess.
M.G. Catanoso, N. Pipitone, C. Salvarani
doaj +1 more source
Management of peripheral arthritis in patients with psoriatic arthritis
Objective. We aimed to compile evidence for the efficacy and safety of therapeutic options for the periph-eral arthritis domain of psoriatic arthritis (PsA) for the revised 2021 Group in Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations. Methods. A working group consisting of clinicians and patient research
Leung, Ying-Ying +28 more
openaire +1 more source
Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor beta-chain [PDF]
Introduction: The Vbeta12-transgenic mouse was previously generated to investigate the role of antigen-specific T cells in collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis. This mouse expresses a transgenic collagen type II (CII)
Burkhardt, H +23 more
core +1 more source
ASSOCIATION BETWEEN CARDIAC LESION AND OTHER CLINICAL MANIFESTATIONSOF ANKYLOSING SPONDYLITIS
Objective: to study associations between the lesion of the heart and aorta and other clinical manifestations and the characteristics of ankylosing spondylitis (AS). Subjects and methods.
Alla Aleksandrovna Godzenko +9 more
doaj +1 more source
Vertebrae Destruction with Cauda Equina Syndrome Secondary to Spinal Gouty Arthritis: A Case Report [PDF]
Gouty arthritis commonly affects peripheral joints and is associated with hyperuricaemia. Spinal manifestations of gouty arthritis are not common, and majority of published articles worldwide were case reports.
Thuraikumar K, Wan KL, Ong KL, Lim SW
doaj +1 more source
A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity [PDF]
Rheumatoid arthritis (RA) is a chronic inflammatory disease with a heritability of 60%. Genetic contributions to RA are made by multiple genes, but only a few gene associations have yet been confirmed.
Klareskog, Lars +31 more
core +1 more source
Chronic peripheral edema in a patient with rheumatoid arthritis
Chronic peripheral edema is a very common yet underestimated problem. It is of utmost importance to investigate various possible causes and understand the pathophysiological mechanisms of chronic peripheral edema in order to determine the optimal treatment.
Breznik, Vesna +2 more
openaire +3 more sources
Methotrexate in the treatment of peripheral arthritis in ulcerative colitis
To evaluate efficacy of methotrexate treatment in peripheral arthritis of ulcerative colitis.We studied 18 patients (10/8 M/F; mean age: 38.90 yrs; range: 21-65 yrs), with peripheral arthritis (14 with polyarticular, 4 with oligoarticular subset) associate ulcerative colitis.
Peluso R +9 more
openaire +5 more sources
Regulation of peripheral inflammation by spinal p38 MAP kinase in rats. [PDF]
Somatic afferent input to the spinal cord from a peripheral inflammatory site can modulate the peripheral response. However, the intracellular signaling mechanisms in the spinal cord that regulate this linkage have not been defined.
David L Boyle +7 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

