American Journal of Hematology, EarlyView.ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
Design and Evaluation of a Handheld Robotic Device for Peripheral Catheterization. [PDF]
J Med Device, 2022 Leipheimer J +3 more
europepmc +1 more source
Influence of contrast media dose and osmolality on the diagnostic performance of contrast fractional flow reserve [PDF]
, 2017 Background—Contrast fractional flow reserve (cFFR) is a method for assessing functional significance of coronary stenoses, which is more accurate than resting indices and does not require adenosine.
Berry, Colin +10 more
core +1 more source
Annals of Neurology, EarlyView.Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones +54 more
wiley +1 more source
[Social representations about pediatric peripheral catheterization from the perspective of the family and nursingRepresentaciones sociales sobre el cateterismo periférico pediátrico en la perspectiva de la familia y la enfermería]. [PDF]
Rev Cuid, 2022 Krempser P +3 more
europepmc +1 more source
Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A phase 2, randomized, sham-controlled trial [PDF]
, 2018 Background -In non-randomized, open-label studies, a transcatheter interatrial shunt device (IASD, Corvia Medical) was associated with lower pulmonary capillary wedge pressure (PCWP), less symptoms, and greater quality of life and exercise capacity in ...
Basuray, Anupam +17 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić +7 more
wiley +1 more source
Research Note: Exploration of Factors that Impede Door-To-Balloon Times [PDF]
, 2010 When experiencing an acute myocardial infarction (AMI), more commonly known as a heart attack, patients need rapid treatment in order to open up and reestablish blood flow within the coronary artery.
Troby, Erin
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis +5 more
wiley +1 more source
Angiopoietin-2 predicts morbidity in adults with Fontan physiology. [PDF]
, 2019 Morbidity in patients with single-ventricle Fontan circulation is common and includes arrhythmias, edema, and pulmonary arteriovenous malformations (PAVM) among others. We sought to identify biomarkers that may predict such complications.
Aboulhosn, Jamil A +8 more
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