Results 51 to 60 of about 715,764 (296)

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Hypnosis and communication reduce pain and anxiety in peripheral intravenous cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a multicentre randomised trial

, 2020
BACKGROUND: Clinicians traditionally warn patients of pain before peripheral i.v. cannulation (PIVC). However, using words related to pain or undesirable experiences can result in greater pain and anxiety.
Bernard, Franck, Musellec, Hervé, Beloeil, Helene, Fusco, Nicolas, Roelants, Fabienne, Watremez, Christine, Boulon, Natacha, Laviolle, Bruno, Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE) group   +8 more
core   +1 more source

Effect of Educational Program about Management of Intravenous Infiltration and Phlebitis on Nurses' Performance in Neonatal Intensive Care Units [PDF]

Port Said Scientific Journal of Nursing
Background: Peripheral venous catheters, which are often used at the critical care units for newborns, may lead to serious complications; the most frequent issues associated with Catheters for peripheral veins implantation are infiltration and Phlebitis.
Fatma Abou elmaati
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

THE FREQUENCY AND CAUSES OF COMPLICATIONS THE PERIPHERAL VEINS CATHETERIZATION [PDF]

Pain, Anaesthesia and Intensive Care, 2020
Катетеризация периферических вен является самой распространенной инвазивной больничной процедурой, которая, однако, может сопровождаться развитием различных осложнений.Целью проведеного исследования была оценка частоты осложнений, связанных с катетеризацией периферических вен, и сравнение двух видов периферических катетеров у хирургических больных ...
openaire   +3 more sources

Ultrasonic Doppler as a guide for feline peripheral arterial catheterization

Journal of Feline Medicine and Surgery
Objectives The study aimed to determine if an ultrasonic Doppler-guided technique (UDGT) leads to improved placement efficacy (time, success) of feline dorsal pedal arterial catheters vs the traditional palpation-guided technique (TPT). Methods
Satoshi Haginoya, Elizabeth J Thomovsky, Hsin-Yi Weng, Paula A Johnson, Aimee C Brooks   +4 more
openaire   +3 more sources

Effects of a Care Package on the Shelf Life and Incidence of the Infection of Central Peripheral Venous Catheter in the Premature Infants Admitted to the NICU

Journal of Client-centered Nursing Care, 2020
Background: Neonates require continuous and reliable intravenous routes to receive fluids, intravenous nutrition, and medications; accordingly, repeated interventions are essential to implant these routes.
Fariba Safaee, Mohammad Kazemian, Leili Borimnejad, Marjan Rasouli   +3 more
doaj  

Mothers’ Experience of Children Peripheral Intravenous Catheterization: a qualitative content analysis [PDF]

Journal of Kerman University of Medical Sciences, 2018
Background: Peripheral intravenous catheterization is one of the most painful procedures in children settings. Based on evidence, most of children do not benefit from pharmacological and non- pharmacological methods of pain management for this procedure ...
Masoumeh Abdolkhaleghi, Lida Nikfarid, Azarakhsh Hosseini, Faezeh Taslimi   +3 more
doaj