Results 131 to 140 of about 15,568 (261)

Sepsis and Antibiotics in Extremely Preterm Infants: Early Empirical Treatment Was Common, While Late‐Onset Sepsis Accounted for Most Cases and Antibiotic Use

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The aim was to investigate the incidence of sepsis and use of antibiotics among extremely preterm infants, given the limited number of population‐based studies examining this. Methods This retrospective study in Eastern Denmark included all liveborn infants from 23 + 0 weeks/days to 27 + 6 weeks/days of gestation from 2019 to 21.
Anna Bjerager Arnesen   +10 more
wiley   +1 more source

Probable sepsis‐associated encephalopathy as a component of multiple organ dysfunction syndrome in a cat with pyothorax

open access: yesAustralian Veterinary Journal, EarlyView.
A 2‐year‐old male neutered domestic shorthair cat with bacterial pyothorax was referred to a tertiary hospital for treatment of sepsis. He met criteria for multiple organ dysfunction syndrome and developed new‐onset neurological dysfunction subsequent to the development of sepsis.
CC Chan, CR Sharp, CJ Boyd
wiley   +1 more source

Improved Peripheral Intravenous Catheter Maintenance by In-Line Mechanical Pulse

open access: yesBioengineering
The World Health Organization (WHO) has identified infections associated with peripheral intravenous catheters (PIVCs) as a major health burden affecting patients across countries and income status categories, meriting particular attention from care ...
Daniel T. DeArmond   +6 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle   +12 more
wiley   +1 more source

Evaluating comfort measures for commonly performed painful procedures in pediatric patients

open access: yesJournal of Pain Research, 2018
Sana Dastgheyb,1 Keith Fishlock,2 Constantine Daskalakis,1 Jami Kessel,3 Paul Rosen2 1Thomas Jefferson University, Philadelphia, PA, 2Nemours Children’s Health System, Wilmington, DE, 3Nationwide Children’s Hospital Columbus, OH, USA ...
Dastgheyb S   +4 more
doaj  

Dose–Response Effect of Glucagon on Glucose, Beta‐Cell Secretion and Metabolism in Healthy Individuals

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Glucagon is a key regulator of glucose and energy metabolism, yet the dose–response effects of glucagon on markers of metabolism in humans are not fully characterised. We investigated the dose‐dependent effects of glucagon on glucose metabolism, β‐cell secretion and markers of hepatic metabolism in healthy adults.
Sophie Betty Brock   +4 more
wiley   +1 more source

Effectiveness of AccuVein® in the success of peripheral intravenous catheterization in adults and elderly patients with difficult access: a randomized controlled clinical trial

open access: yes
Introdução: A cateterização intravenosa periférica em pacientes com acesso intravenoso difícil pode ser desafiadora. Diante disso é recomendada a utilização de tecnologias de visualização da rede venosa para ampliar a assertividade e diminuir o tempo de
Bittencourt, Isaiane Santos [UNIFESP]
core  

Acute GIP and GLP‐1 Administration Exerts Differential Metabolic Effects in Totally Pancreatectomised Individuals

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims While being recognised for stimulating pancreatic insulin secretion, GIP and GLP‐1 exert various extrapancreatic effects relevant in the context of incretin‐based therapies. Here, we evaluated the extrapancreatic effects of GIP and GLP‐1, separately and combined, on postprandial physiology in totally pancreatectomised individuals ...
Liva S. L. Krogh   +8 more
wiley   +1 more source

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