Results 71 to 80 of about 114,544 (293)

International symposium on peripheral nerve repair and regeneration and 2nd club Brunelli meeting [PDF]

, 2010
The International Symposium "Peripheral Nerve Repair and Regeneration and 2nd Club Brunelli Meeting" was held on December 4-5, 2009 in Turin, Italy (Organizers: Bruno Battiston, Stefano Geuna, Isabelle Perroteau, Pierluigi Tos).
Geuna Stefano, Turgut Mehmet
core   +2 more sources

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Iron role paradox in nerve degeneration and regeneration

Physiological Reports
Iron accumulates in the neural tissue during peripheral nerve degeneration. Some studies have already been suggested that iron facilitates Wallerian degeneration (WD) events such as Schwann cell de‐differentiation.
Samira Bolandghamat, Morteza Behnam‐Rassouli   +1 more
doaj   +1 more source

Fas ligand regulate nerve injury and repair by affecting AKT, β-catenin, and NF-κB pathways

IBRO Neuroscience Reports
Objective: To investigate the regulatory effect of Fas-L on the repair and regeneration of peripheral extension injury in rats. Methods: This study aimed to explore the effects of Fas-L on apoptosis and axonal regeneration of dorsal root ganglion (DRG ...
Yiyue Zhou, Yi Yao, Yumei Feng, Zhiyuan Qiu, Shixian Luo, Xinyu Shi, Dandan Gu, Maorong Jiang, Min Cai, Dengbing Yao   +9 more
doaj   +1 more source

An examination of walking track analysis footprints of right-side unoperated limbs in rats prior to and following peripheral nerve injury and PEG fusion repair [PDF]

, 2018
Peripheral nerve injury can result in long-lasting functional deficits in humans due to mammals’ limited axon regenerative capacity. PEG fusion is a defined technique that fuses injured axons, resulting in morphological and electrophysiological ...
Jagannath, Karthik
core   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

Investigation for the correlation between brain injury and injured ipsilateral sciatic nerve regeneration in a rat model

Journal of Integrative Neuroscience, 2019
Previous studies showed that brain trauma promotes repair of peripheral nerve injury by reducing scar in nerve endings. The effect of brain injury at different locations on ipsilateral rat sciatic nerve regeneration in Sprague-Dawley rats was found to ...
Haoqi Wang, Jianjun Ma, Xinze He, Qiang Xie, Yuting Fu, Pei Wang   +5 more
doaj   +1 more source

Storage and allogeneic transplantation of peripheral nerve using a green tea polyphenol solution in a canine model [PDF]

, 2010
Background In our previous study, allogeneic-transplanted peripheral nerve segments preserved for one month in a polyphenol solution at 4°C could regenerate nerves in rodents demonstrated the same extent of nerve regeneration as isogeneic fresh nerve ...
Ken Nakayama, Ryosuke Kakinoki, Ryosuke Ikeguchi, Tomoyuki Yamakawa, Soichi Ohta, Satoshi Fujita, Takashi Noguchi, Scott Duncan, Suong-Hyu Hyon, Takashi Nakamura   +9 more
core   +2 more sources

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source