Results 111 to 120 of about 1,092,875 (381)
Purinergic signalling: past, present and future [PDF]
, 2009 The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
Burnstock, G
core +1 more source
Advanced Healthcare Materials, EarlyView.The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden +5 more
wiley +1 more source
ProceedingsNeurological disorders are heterogeneous diseases that affect the body’s autonomic, peripheral and central nervous system [...]
Ilaria Antonia Vitale +2 more
doaj +1 more source
Neuron-Schwann cell interactions in peripheral nervous system homeostasis, disease, and preclinical treatment [PDF]
, 2023 Júlia Teixeira Oliveira +3 more
openalex +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
Advanced Healthcare Materials, EarlyView.What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell +5 more
wiley +1 more source
B VITAMIN COMPLEX IN THE TREATMENT OF NEUROLOGICAL DISORDERS
Медицинский совет, 2016 The spectrum of the nervous system diseases in which administration of B vitamins is pathogenetically justified, especially thiamine, pyridoxine and cyanocobalamin, is varied.
G. N. BEL’SKAYA +4 more
doaj +1 more source
Regulation of Heart Beats by the Autonomous Nervous System in Health and Disease: Point-Process-Theory based Models and Simulation [V-I] [PDF]
arXiv, 2019 We have advanced a point-process based framework for the regulation of heart beats by the autonomous nervous system and analyzed the model with and without feedback. The model without feedback was found amenable to several analytical results that help develop an intuition about the way the heart interacts with the nervous system.
arxiv
Prion pathogenesis and secondary lymphoid organs (SLO): Tracking the SLO spread of prions to the brain [PDF]
, 2012 Prion diseases are subacute neurodegenerative diseases that affect humans and a range of domestic and free-ranging animal species. These diseases are characterized by the accumulation of PrP(Sc), an abnormally folded isoform of the cellular prion protein
Mabbott, N. A.
core +1 more source
Actuated Hydrogel Platforms To Study Brain Cell Behavior
Advanced Healthcare Materials, EarlyView.The complex and dynamic viscoelastic properties of the brain underpin neural plasticity and overall function. Actuating hydrogel platforms support mechanistic research to elucidate how brain cells respond to dynamic microenvironments. This study reviews the mechanobiology of the brain and its impact on brain function in health and disease and describes
Kirill E. Zhurenkov +3 more
wiley +1 more source
A reaction-diffusion model for the progression of Parkinson's disease [PDF]
arXiv, 2017 The temporal and spatial development of Parkinson's disease has been characterised as the progressive formation of {\alpha}-synuclein aggregations through susceptible neuronal pathways. This article describes a new model for this progression mechanism in which Parkinsonian damage moves over time through the nervous system by the combined effect of the ...
arxiv