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Elucidating the specific mechanisms of the gut-brain axis: the short-chain fatty acids-microglia pathway. [PDF]
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Gene Therapy for Peripheral Nervous System Diseases
Current Gene Therapy, 2007Peripheral nerve diseases, also known as peripheral neuropathies, affect 15-20 million of Americans and diabetic neuropathy is the most common condition. Currently, the treatment of peripheral neuropathies is more focused on managing pain rather than providing permissive conditions for regeneration.
Thais Federici, Nicholas M. Boulis
openaire +3 more sources
Autoimmune diseases of the peripheral nervous system
Autoimmunity Reviews, 2012Autoimmune-mediated diseases targeting the peripheral nerve represent a group of disorders often associated with high clinical disability. At present, therapeutic options are limited. The application of innovative and cutting-edge technologies to the study of immune-mediated disorders of the peripheral nervous system (PNS) have generated a better ...
Helmar C. Lehmann +2 more
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Central and Peripheral Nervous System Diseases
2007Immune diseases of the central and peripheral nervous system constitute an heterogeneous group of disorders which share a significative implication of the immune system in pathophysiology. Multiple sclerosis (MS), Guillain Barre syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) are considered of autoimmune origin, with an ...
Dorothée Chabas +2 more
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Peripheral nervous system diseases of surgical interest
2001Injuries to the peripheral nervous system that hold surgical interest are: traumatic and iatrogenic lesions, entrapment and canicular injuries, and tumoral injuries.
Pierpaolo Lunardi +2 more
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Antibodies to glycolipids in demyelinating diseases of the human peripheral nervous system
Chemistry and Physics of Lipids, 1986Antibodies to complex glycolipids occur in patients with a variety of diseases of the peripheral nervous system. Many patients with demyelinating neuropathy occurring in association with IgM paraproteinemia have a monoclonal antibody that reacts with a carbohydrate determinant shared between sulfate-3-glucuronyl paragloboside (SGPG), the myelin ...
Amjad A. Ilyas +2 more
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Peripheral nervous system manifestations of rheumatological diseases
Journal of the Neurological Sciences, 2021Rheumatological diseases result in immune-mediated injury to not only connective tissue, but often components of the peripheral nervous system. These overlap conditions can be broadly categorized as peripheral neuropathies and overlap myositis. The peripheral neuropathies are distinctive as many have unusual presentations such as non-length-dependent ...
Kelly G. Gwathmey, Kelsey Satkowiak
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Amyloid and peripheral nervous system disease
Clinical Neurology and Neurosurgery, 1994The peripheral nervous system can be involved in the following amyloid deposition diseases. (1) Amyloid deposition composed of beta 2-microglobulin in patients on long term hemodialysis causing a carpal tunnel syndrome; (2) deposition of light chain immunoglobulin derived amyloid leading to polyneuropathy, carpal tunnel syndrome and autonomic nervous ...
J. Haan, W.G. Peters
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Current Medicinal Chemistry, 2010
In regenerative medicine, stem cells are currently considered ideal candidates for the treatment of diseases and injuries of the nervous system, for which, at present, there are no effective treatments.
A. Orlacchio +3 more
semanticscholar +1 more source
In regenerative medicine, stem cells are currently considered ideal candidates for the treatment of diseases and injuries of the nervous system, for which, at present, there are no effective treatments.
A. Orlacchio +3 more
semanticscholar +1 more source