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Paraneoplastic Diseases of the Peripheral Nervous System

2016
Peripheral nervous system involvement is the most commonly observed condition in patients with paraneoplastic neurological syndromes (PNS), and its clinical manifestations are highly heterogeneous. The peripheral nervous system can be variously involved, but the most frequently affected sites are the dorsal ganglia and presynaptic nerve endings of the ...
Anna Grisold   +2 more
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T lymphocyte autoimmunity in peripheral nervous system autoimmune disease

Agents and Actions, 1986
Autoaggressive T cells specific for the PNS myelin P2 protein play a central role in the initiation of EAN in the Lewis rat, although there is as yet no direct experimental evidence that the T cells can themselves mediate demyelination in vivo. However, the striking similarities in the pathogenesis of EAN and the Guillain-Barre syndrome suggest that T ...
Richard Meyermann   +2 more
openaire   +3 more sources

Peripheral Nervous System (PNS) Myelin Diseases

Cold Spring Harbor Perspectives in Biology
This is a review of inherited and acquired causes of human demyelinating neuropathies and a subset of disorders that affect axon-Schwann cell interactions. Nearly all inherited demyelinating neuropathies are caused by mutations in genes that are expressed by myelinating Schwann cells, affecting diverse functions in a cell-autonomous manner.
Steven S, Scherer, John, Svaren
openaire   +2 more sources

B vitamins and diseases of the peripheral nervous system

S.S. Korsakov Journal of Neurology and Psychiatry
Various diseases of the peripheral nervous system are associated with metabolic disorders of B vitamins. A lack of neurotropic vitamins, which began in the early stages of the development of a bacterial disease, led to its more rapid development. The article analyzes data on B vitamin deficiency in the pathogenesis of the most dangerous diseases of the
P.R. Kamchatnov   +4 more
openaire   +2 more sources

Peripheral nervous system diseases of surgical interest

2001
Injuries to the peripheral nervous system that hold surgical interest are: traumatic and iatrogenic lesions, entrapment and canicular injuries, and tumoral injuries.
Pierpaolo Lunardi   +2 more
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Peripheral nervous system disease in Systemic Lupus Erythematosus

2019
Objectives: In a multi-ethnic/racial, prospective SLE inception cohort, to determine the frequency, clinical characteristics, associations and outcomes in different types of peripheral nervous system (PNS) disease. Methods: Patients were evaluated annually for 19 neuropsychiatric (NP) events including seven types of PNS disease.
Hanly, John   +5 more
openaire   +2 more sources

Early peripheral nervous system manifestations of infantile Krabbe disease

Pediatric Neurology, 2003
Early infantile Krabbe disease is relatively frequent in the Muslim-Arab population in Israel. It can be easily diagnosed when it presents with the classic clinical picture characterized by central nervous system manifestations of spasticity, irritability, motor regression and seizures associated with a positive family history.
Dov Soffer   +5 more
openaire   +2 more sources

Water channel proteins in the peripheral nervous system in health and disease

Molecular Aspects of Medicine, 2012
The expression and function of aquaporins (AQPs) in the peripheral nervous system is a relatively under-investigated subject. Since the original description of AQP1 mRNA expression in the trigeminal ganglion in 2004, there has been significant progress in describing the expression, regulation and function of AQPs in the peripheral nervous system. Three
Tonghui Ma   +3 more
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Intermediate filaments in peripheral nervous system: Their expression, dysfunction and diseases

Revue Neurologique, 2016
Characteristics of the intermediate filament proteins (IFPs) expressed during the development and cell differentiation of peripheral neurons are here reviewed. Neurofilament triplet proteins (NFPs), peripherin, α-internexin, synemin, syncoilin, nestin, vimentin and glial fibrillary acidic protein (GFAP) are each produced by different genes.
Zhenlin Li   +4 more
openaire   +3 more sources

Antibodies to glycolipids in demyelinating diseases of the human peripheral nervous system

Chemistry and Physics of Lipids, 1986
Antibodies to complex glycolipids occur in patients with a variety of diseases of the peripheral nervous system. Many patients with demyelinating neuropathy occurring in association with IgM paraproteinemia have a monoclonal antibody that reacts with a carbohydrate determinant shared between sulfate-3-glucuronyl paragloboside (SGPG), the myelin ...
Amjad A. Ilyas   +2 more
openaire   +3 more sources

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