Results 71 to 80 of about 504,107 (354)

Clinical and electrodiagnostic findings in a cohort of 61 dogs with peripheral nervous system diseases - a retrospective study [PDF]

Pakistan Veterinary Journal, 2014
The electrodiagnostic examination provides the basis for a diagnostic workup in diseases involving nerve roots, peripheral nerves, neuromuscular junctions and muscles in humans and animals.
EG Giza, JE Nicpon and MA Wrzosek
doaj  

Defining the organizational structure of dopamine and muscarninic acetylcholine receptors [PDF]

, 2015
No abstract ...
Alvarez-Curto, Elisa, Caltabiano, Gianluigi Caltabiano, Liste, María José Varela, Marsango, Sara, Milligan, Graeme   +4 more
core   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source

Clinical analysis on two patients with N-hexane toxic peripheral neuropathy misdiagnosed as chronic inflammatory demyelinating polyradiculoneuropathy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To investigate the clinical and neuropathological features of N-hexane toxic peripheral neuropathy which was misdiagnosed as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
Yi LI, Ling-chao MENG, He LÜ, Wei ZHANG, Zhao-xia WANG, Jing LIU, Yue-huan ZUO, Yun YUAN   +7 more
doaj  

Collagen VI in healthy and diseased nervous system

Disease Models & Mechanisms, 2018
Collagen VI is a major extracellular matrix protein exerting a number of functions in different tissues, spanning from biomechanical to regulatory signals in the cell survival processes, and playing key roles in maintaining the stemness or determining ...
Ilaria Gregorio, Paola Braghetta, Paolo Bonaldo, Matilde Cescon   +3 more
doaj   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

Reviving hope – the journey of diagnosing and treating Guillain-Barré syndrome

Pediatria Polska
The Guillain-Barré syndrome (GBS) is a rare but serious neurological condition that continues to pose diagnostic and therapeutic challenges, particularly in paediatrics.
Anna Oleszczuk, Julia Kozieł, Szymon Kosmala, Noemi Kufrejska, Paweł Hawranik, Katarzyna Jurkiewicz, Marcelina Kurek, Magdalena Chrościńska-Krawczyk   +7 more
doaj   +1 more source

Changes in sympathetic activity in prion neuroinvasion

Neurobiology of Disease, 2010
Prion diseases are neurodegenerative diseases affecting humans and animals in which the infectious agent or prion is PrPres, a protease-resistant conformer of the cell protein PrP. The natural transmission route of prion diseases is peripheral infection,
Gianpietro Bondiolotti, Giuseppe Rossoni, Maria Puricelli, Elena Formentin, Barbara Lucchini, Giorgio Poli, Wilma Ponti, Silvio R. Bareggi   +7 more
doaj   +1 more source

The Molecular Pathology of Prion Diseases [PDF]

, 2004
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Herms, Jochen, Kretzschmar, Hans A., Vassallo, Neville   +2 more
core  

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source