Results 71 to 80 of about 1,092,875 (381)

An Integrated View on Neuronal Subsets in the Peripheral Nervous System and Their Role in Immunoregulation

Frontiers in Immunology, 2021
The peripheral nervous system consists of sensory circuits that respond to external and internal stimuli and effector circuits that adapt physiologic functions to environmental challenges.
Manuel O. Jakob, Michael Kofoed-Branzk, Divija Deshpande, Shaira Murugan, Christoph S. N. Klose   +4 more
doaj   +1 more source

Molecular Insights into Appetite Control and Neuroendocrine Disease as Risk Factors for Chronic Diseases in Western Countries [PDF]

, 2013
Environmental factors such as stress, anxiety and depression are important to consider with the global increase in chronic diseases such as cardiovascular diseases, cancer, stroke, obesity, diabetes and neurodegenerative diseases.
Creegan, Rhona, Lim, W. L. F., Martins, I J, Martins, Ralph   +3 more
core   +2 more sources

Nerve Biopsy in Peripheral Neuropathies: Not All Water Is under the Bridge

Brain Sciences, 2021
Sural nerve biopsy has long been a valuable diagnostic tool for the study of peripheral neuropathies, although the recent introduction of non-invasive techniques (e.g., neuroimaging techniques, skin biopsy) and advanced genetic and immunological testing ...
Marco Luigetti, Andrea Di Paolantonio
doaj   +1 more source

The Cutaneous Biopsy for the Diagnosis of Peripheral Neuropathies: Meissner’s Corpuscles and Merkel’s Cells [PDF]

, 2018
Cutaneous biopsy is a complementary method, alternative to peripheral nerve biopsy, for the analysis of nerve involvement in peripheral neuropathies, systemic diseases, and several pathologies of the central nervous system.
Alba, Elda, Cobo, Juan L., Cobo, Ramón, Feito, Jorge, García-Mesa, Yolanda, García-Piqueras, Jorge, García-Suárez, Olivia, Salvo, Giuseppina, Vega, José A.   +8 more
core   +2 more sources

Efficacy of AAV serotypes to target Schwann cells after intrathecal and intravenous delivery [PDF]

, 2021
Diseases of the nervous system; Myelin biology and repair; Peripheral nervous systemEnfermedades del sistema nervioso; Biología y reparación de la mielina; Sistema nervioso periféricoMalalties del sistema nerviós; Biologia i reparació de la mielina ...
Bosch, A., Christodoulou, C., Kagiava, A., Kleopa, K. A., Leal-Julià, Marc, Richter, J., Sargiannidou, I., Tryfonos, C., Universitat Autònoma de Barcelona   +8 more
core   +2 more sources

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source

Preclinical Deposition of Pathological Prion Protein in Muscle of Experimentally Infected Primates [PDF]

, 2010
Prion diseases are transmissible fatal neurodegenerative disorders affecting humans and animals. A central step in disease progression is the accumulation of a misfolded form (PrPSc) of the host encoded prion protein (PrPC) in neuronal and non-neuronal ...
Aguzzi, Adriano, Bodemer, Walter, Geissen, Markus, Glatzel, Markus, Kaup, Franz-Josef, Krasemann, Susanne, Morel, Nathalie, Neumann, Melanie, Schulz-Schaeffer, Walter   +8 more
core   +4 more sources

Evidence of blood–brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro, Neetha Paul Eduthan, Mellad M. Khoshnood, Saba Jafarpour, Natalie K. Boyd, Benjamin N. Vogel, Lina Nguyen, Lilia Kazerooni, Eleanor Britton, Hannah R. Lyford, Matthew D. Galbraith, Angela L. Rachubinski, Joaquin M. Espinosa   +12 more
wiley   +1 more source

Evidence of Oligoclonal Bands Does Not Exclude Non-Inflammatory Neurological Diseases

Diagnostics, 2020
Cerebrospinal fluid analysis is an essential part of the diagnostic workup in various neurological disorders. Evidence of an intrathecal immunoglobulin synthesis, as demonstrated by Reiber’s diagram or the more sensitive oligoclonal bands (OCB), are ...
Katharina Pannewitz-Makaj, Ulrich Wurster, Konstantin Fritz Jendretzky, Stefan Gingele, Kurt-Wolfram Sühs, Martin Stangel, Thomas Skripuletz, Philipp Schwenkenbecher   +7 more
doaj   +1 more source

Bimanual proprioception: are two hands better than one? [PDF]

J Neurophysiol. 2014 Mar;111(6):1362-8, 2013
Information about the position of an object that is held in both hands, such as a golf club or a tennis racquet, is transmitted to the human central nervous system from peripheral sensors in both left and right arms. How does the brain combine these two sources of information?
arxiv   +1 more source