Pluripotent Stem Cell-Derived Teratoma presents an embryonic neoplastic niche for in vivo studies of Neuroectodermal Childhood Tumors [PDF]
, 2012 Therapy-resistance and relapse remain problematic in many cancer patients, despite the advancement in anti-cancer therapies. There is a constant need of developing new anti-cancer drugs to combat tumors keeping in mind also the increasing incidence
Jamil, Seema
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Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. [PDF]
, 2014 Ewing sarcoma is the second-most-common bone cancer in children. Driven by an oncogenic chromosomal translocation that results in the expression of an aberrant transcription factor, EWS/FLI, the disease is typically aggressive and micrometastatic upon ...
Beckerle, Mary C +8 more
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Utility of Transmission Electron Microscopy in Small Round Cell Tumors [PDF]
Journal of Pathology and Translational Medicine, 2015 Small round cell tumors (SRCTs) are a heterogeneous group of neoplasms composed of small, primitive, and undifferentiated cells sharing similar histology under light microscopy.
Na Rae Kim, Seung Yeon Ha, Hyun Yee Cho
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A molecular biology and phase II trial of lapatinib in children with refractory CNS malignancies: a pediatric brain tumor consortium study. [PDF]
, 2013 High expression of ERBB2 has been reported in medulloblastoma and ependymoma; EGFR is amplified and over-expressed in brainstem glioma suggesting these proteins as potential therapeutic targets. We conducted a molecular biology (MB) and phase II study to
Blaney, Susan M. +11 more
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Journal of the Egyptian National Cancer Institute, 2014 Neonatal tumors comprise less than two percent of childhood malignancies. Most are solid tumors, most common histologies being teratoma and neuroblastoma.
Shikha Goyal +3 more
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Peripheral primitive neuroectodermal tumor of the small bowel mesentery: Report of a case [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2015 Introduction. Primitive neuroectodermal tumor or Ewing’s sarcoma is a tumor of undifferentiated small round cells that arise from the soft tissues, and is believed to be of neural origin. It occurs most often in children, followed by adolescents
Marić Helena +5 more
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Evidence of a dual histogenetic pathway of sacrococcygeal teratomas [PDF]
, 2016 Aims Sacrococcygeal teratomas are rare tumours that occur most frequently in neonates, although adult cases also occur. The molecular pathogenesis of these tumours and their long-term prognosis is uncertain.
Cheng, Liang +10 more
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Primary primitive neuroectodermal tumor of the kidney
Indian Journal of Pathology and Microbiology, 2018 Renal primitive neuroectodermal tumor (PNET) is a rare entity. It should be differentiated from other primary renal malignancies. The differentiation of the malignant small round cell tumors may be challenging; however, it is essential for better ...
Sunil Vitthalrao Jagtap +4 more
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A rare case of a peripheral Ewing sarcoma primitive neuroectodermal tumor of pelvic origin
Radiology Case Reports, 2023 Primitive neuroectodermal tumors (PNET) represent malignant neuroectodermal tumors composed of small round cells. They can be differentiated between originating from the peripheral nervous system or the central nervous system. Peripheral PNET (pPNET) can
Erinie Mekheal, MD +5 more
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Rosette‐like structures in the spectrum of spitzoid tumors [PDF]
, 2013 Background Spitz nevi demonstrate a diverse spectrum of morphologies. Recently, there have been two reported examples of Spitz nevi with rosette‐like structures similar to Homer‐Wright rosettes.
Arps, David P. +3 more
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