Results 71 to 80 of about 14,856,300 (187)

Simultaneous inhibition of pan-phosphatidylinositol-3-kinases and MEK as a potential therapeutic strategy in peripheral T-cell lymphomas

Haematologica, 2013
Peripheral T-cell lymphomas are very aggressive hematologic malignancies for which there is no targeted therapy. New, rational approaches are necessary to improve the very poor outcome in these patients.
Esperanza Martín-Sánchez, Socorro M. Rodríguez-Pinilla, Margarita Sánchez-Beato, Luis Lombardía, Beatriz Domínguez-González, Diana Romero, Lina Odqvist, Pablo García-Sanz, Magdalena B. Wozniak, Guido Kurz, Carmen Blanco-Aparicio, Manuela Mollejo, F. Javier Alves, Javier Menárguez, Fernando González-Palacios, José Luis Rodríguez-Peralto, Pablo L. Ortiz-Romero, Juan F. García, James R. Bischoff, Miguel A. Piris   +19 more
doaj   +1 more source

An update on the management of peripheral T-cell lymphoma and emerging treatment options

, 2011
Adrienne A Phillips1, Colette Owens2, Sangmin Lee1, Govind Bhagat31Division of Medical Oncology, Department of Medicine, 2Division of General Medicine, Department of Medicine, 3Department of Pathology and Cell Biology, Columbia University Medical Center ...
Lee S, Bhagat G, Owens C, Phillips AA
core  

Peripheral T cell lymphoma

Indian Journal of Medical Research, 2018
Aude-Marie Fourmont, Mathieu Bellal
openaire   +3 more sources

Peripheral Lymphocytosis in Angioimmunoblastic T-cell Lymphoma

International Journal of Advanced Medical and Health Research
Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive and unique type of T-cell lymphoma. Patients typically present with constitutional B symptoms, generalized lymphadenopathy, hepatosplenomegaly, cytopenias, and rash.
C. Selvapriya, Nidhya Ganesan, Sakthisankari Shanmugasundaram, Narmadha Rathinasamy, Prasanna Nedungadi Kumar   +4 more
doaj   +1 more source

New developments in the treatment of peripheral T-cell lymphoma – role of Belinostat

, 2015
Peter Reimer Clinic for Hematology, Medical Oncology and Stem Cell Transplantation, Evangelisches Krankenhaus Essen-Werden gGmbH, Essen, Germany Abstract: Peripheral T-cell lymphomas (PTCL) represent a heterogeneous group of rare malignancies that with ...
Reimer P
core  

Therapeutic challenges in peripheral T-cell lymphoma

Molecular Cancer
Peripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of hematological malignancies. Compared to our knowledge of B-cell tumors, our understanding of T-cell leukemia and lymphoma remains less advanced, and a significant number of patients ...
Yunpeng Luan, Xiang Li, Yunqi Luan, Junyu Luo, Qinzuo Dong, Shili Ye, Yuejin Li, Yanmei Li, Lu Jia, Jun Yang, Dong-Hua Yang   +10 more
doaj   +1 more source

Successful Bridging to Allogeneic Transplantation With Valemetostat in Two Refractory/relapsed Peripheral T-cell lymphoma patients

Mediterranean Journal of Hematology and Infectious Diseases
We report the case of 2 patients with relapsed/refractory peripheral T-cell lymphoma treated with valemetostat tosilate, a selective dual inhibitor of histone-lysine N-methyltransferases enhancer of zeste homolog 1 and 2, and subsequently bridged to ...
Gianmarco Bagnato, Vittorio Stefoni, Alessandro Broccoli, Lisa Argnani, Cinzia Pellegrini, Beatrice Casadei, Francesca Bonifazi, Pier Luigi Zinzani   +7 more
doaj   +1 more source

Unveiling the Enigma: Plasma Cell Leukaemia Presenting with Flower-like Cells, Mimicking Adult T-cell Leukaemia – A Rare Diagnostic Conundrum

Prague Medical Report
Peripheral plasma cell leukaemia (PCL) is a rare hematologic malignancy that can pose diagnostic challenges due to its resemblance to other conditions such as adult T-cell leukaemia/lymphoma (ATLL) or dissemination lymphoma in peripheral blood.
Anurag Singh, Gyanendra Singh
doaj   +1 more source

Primary Cutaneous Extranodal Natural Killer/T-Cell Lymphoma Misdiagnosed as Peripheral T-Cell Lymphoma: The Importance of Consultation/Referral and Inclusion of EBV In Situ Hybridization for Diagnosis

, 2017
Background: Primary cutaneous T-cell lymphomas (CTCL) are heterogenous extranodal non-Hodgkin lymphomas including a few distinct and provisional entities.
Win, Khin Than;Liau, Jau-Yu;Chen, Bo-Jung;Takata, Katsuyoshi;Chen, Chiao-Yun;Li, Chi-Cheng;Hsiao, Cheng-Hsiang;Chuang, Shih-Sung, 廖肇裕;李啟誠   +1 more
core   +1 more source

The RNA sequencing results revealed the expression of different genes and signaling pathways during chemotherapy resistance in peripheral T-cell lymphoma

BMC Medical Genomics
Background Peripheral T-cell lymphoma (PTCL) is a subtype of non-Hodgkin's lymphoma that occurs primarily at extranodal sites and is commonly treated using chemotherapy and radiotherapy.
Yunyi Lan, Wei Tao, Luyao Ma, Xiaoxiong Wang, Hongsheng Li, Yaxi Du, Ruijiao Yang, Shunxian Wu, Yingxin Ou, Xin Liu, Yunchao Huang, Yongchun Zhou   +11 more
doaj   +1 more source