Results 251 to 260 of about 139,987 (302)

BCL‐2 and MCL1 co‐inhibition enhances glucocorticoid therapy in preclinical models of infant KMT2A‐rearranged acute lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Mawar Karsa, Ayu Karsa, Dayna Spurling, Lin Xiao, Emma Ronca, Angelika Bongers, Weiman Gao, Andrew J. Gifford, Ali El‐Ayoubi, Laurence C. Cheung, Rishi S. Kotecha, Richard B. Lock, Charis E. Teh, Guillaume Lessene, Murray D. Norris, Andrew Wei, Michelle Haber, Michelle J. Henderson, Donia M. Moujalled, Klaartje Somers   +19 more
wiley   +1 more source

Erratum for the Research Article, "Cooperative role of distinctive TP53 and PTEN combined loss in the peripheral T cell lymphoma-GATA3 molecular subgroup" by W.G. Lone <i>et al</i>.

Sci Adv
europepmc   +1 more source

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Peripheral T‐cell lymphomas

Hematological Oncology, 2023
AbstractThe treatment of peripheral T‐cell lymphomas is challenging, as they often display a severe prognosis and lack effective treatment strategies. We will try to answer three burning questions: can we differentiate the initial treatment based on the histotype and the clinical presentation of peripheral T‐cell lymphoma patients?
Broccoli A., Zinzani P. L.
openaire   +3 more sources

Clinical differences between nasal and extranasal natural killer/T-cell lymphoma: a study of 136 cases from the International Peripheral T-Cell Lymphoma Project

Blood, 2009
Among 1153 new adult cases of peripheral/T-cell lymphoma from 1990-2002 at 22 centers in 13 countries, 136 cases (11.8%) of extranodal natural killer (NK)/T-cell lymphoma were identified (nasal 68%, extranasal 26%, aggressive/unclassifiable 6%).
Wing-Yan Au, Tanin Intragumtornchai, Won-Seog Kim   +2 more
exaly   +2 more sources

Pathogenesis of Peripheral T Cell Lymphoma

Annual Review of Pathology: Mechanisms of Disease, 2018
Peripheral T cell lymphomas (PTCLs) are highly heterogeneous tumors, displaying distinct clinical and biological features. The pathogenesis and normal counterpart of such entities have been elusive for decades. Recent studies have, however, disclosed key mechanisms of peripheral T cell transformation, including (a) the deregulation of signaling ...
Marco Pizzi, Elizabeth Margolskee, Giorgio Inghirami   +2 more
exaly   +4 more sources

Peripheral T-cell lymphoma

Cancer and Metastasis Reviews, 1988
Since the discovery of human T-cell leukemia virus type 1 (HTLV-1) in patients with adult T-cell leukemia/lymphoma (ATLL), malignant neoplasms of mature (peripheral) T lymphocytes have attracted a great deal of attention. This type of neoplasm is more common in Japan than in Western countries, and may show distinct clinical pictures such as ...
S, Watanabe, K, Mukai, M, Shimoyama
openaire   +2 more sources

The spectrum of peripheral T-cell lymphomas

Current Opinion in Hematology, 2009
This review summarizes recent progress that has advanced our understanding of the pathobiology and prognosis of peripheral T-cell lymphomas including the changes introduced to the updated World Health Organization classification of lymphoid neoplasms.The International Peripheral T-Cell Lymphoma Project was a large collaborative project, highlighting ...
Hilary, O'leary, Kerry J, Savage
openaire   +2 more sources

Peripheral T-Cell Lymphoma of the Scrotum

Acta Haematologica, 2009
Primary lymphoma of the scrotum is rare. We report a case of primary immunoblastic lymphoma of the scrotum in a homosexual who was negative for antibodies to human immunodeficiency virus. Immunoperoxidase stains of paraffin-embedded tissue were consistent with a T-cell phenotype.
D C, Doll, A A, Diaz-Arias
openaire   +2 more sources

Romidepsin for peripheral T-cell lymphoma

Expert Review of Hematology, 2013
Peripheral T-cell lymphoma (PTCL) is comprised of a rare heterogeneous group of diseases with diverse clinical presentations; however outcomes associated with conventional chemotherapy are generally poor in the majority of patients. Newer approaches, which include dose-intensification and agents with novel mechanisms of action, are needed to improve ...
Amit, Khot, Michael, Dickinson, H Miles, Prince   +2 more
openaire   +2 more sources

Peripheral T Cell Lymphoma: an Overview

Leukemia & Lymphoma, 1990
Peripheral T cell lymphoma (PTCL) is a term that encompasses a wide range of histological subtypes of Non-Hodgkin's lymphoma which arise from mature or post-thymic T lymphocytes. These tumours account for 10-20% of all cases of non-Hodgkin's lymphoma in the Western World.
P A, Hall, M A, Richards
openaire   +2 more sources