Results 1 to 10 of about 840,001 (183)

Peripheral Vascular Disease

Primary Care: Clinics in Office Practice
Peripheral artery disease is most often caused by atherosclerosis. Arterial insufficiency from atherosclerotic blockages in the limbs can impair walking distance and put patients with severe disease at risk of limb loss. Management of the disease centers around early diagnosis, supervised exercise therapy and lifestyle modification, optimizing medical ...
Gul F, Janzer SF.
europepmc   +3 more sources

Peripheral Vascular Disease

Home Healthcare Now, 2020
Peripheral vascular disease (PVD) is a leading health concern in the United States, with an estimated prevalence of 8.5 million. The incidence of PVD is growing due to increasing rates of obesity and diabetes, as well as an aging population. Peripheral vascular disease is categorized as either venous, arterial, or mixed.
Constance F, Swenty, Mellisa, Hall
openaire   +6 more sources

Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis

Scientific Reports, 2021
Inflammation, vascular smooth muscle cell apoptosis and oxidative stress are believed to play important roles in abdominal aortic aneurysm (AAA) pathogenesis.
Smriti Murali Krishna, Jiaze Li, Yutang Wang, Corey S. Moran, Alexandra Trollope, Pacific Huynh, Roby Jose, Erik Biros, Jianxing Ma, Jonathan Golledge   +9 more
doaj   +1 more source

Serum angiopoietin-1 concentration does not distinguish patients with ischaemic stroke from those presenting to hospital with ischaemic stroke mimics

BMC Cardiovascular Disorders, 2022
Background A previous study found that circulating angiopoietin-1 (angpt-1) concentrations were significantly lower in patients who had a recent ischaemic stroke compared to healthy controls.
Joseph V. Moxon, Ann-Katrin Kraeuter, James Phie, Sheryl Juliano, Georgina Anderson, Glenys Standley, Cindy Sealey, Richard P. White, Jonathan Golledge   +8 more
doaj   +1 more source

Access Site Related Vascular Complications following Percutaneous Cardiovascular Procedures

Journal of Cardiovascular Development and Disease, 2021
Vascular access site complications (ASC) are among the most frequent complications of percutaneous cardiovascular procedures (PCP) and are associated with adverse outcome and high resources utilization. In this prospective study, we investigated patients
Johanna Hetrodt, Christiane Engelbertz, Katrin Gebauer, Jacqueline Stella, Matthias Meyborg, Eva Freisinger, Holger Reinecke, Nasser Malyar   +7 more
doaj   +1 more source

Safety and efficacy of larval therapy on treating leg ulcers: a protocol for systematic review and meta-analysis

BMJ Open, 2020
Introduction Leg ulcers (LUs) not only seriously affect life and work of patients, but also bring huge economic burden to the society. As a potential underused biological debridement, larval therapy provides help for the treatment of LUs.
Xiao Yang, Weijing Fan, Baozhong Yang, Xiaoming Hu, Chenyan Shi, Guobin Liu   +5 more
doaj   +1 more source

Kallikrein‐1 Blockade Inhibits Aortic Expansion in a Mouse Model and Reduces Prostaglandin E2 Secretion From Human Aortic Aneurysm Explants

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Abdominal aortic aneurysm (AAA) is an important cause of mortality in older adults. The kinin B2 receptor agonist, bradykinin, has been implicated in AAA pathogenesis through promoting inflammation.
Corey S. Moran, Erik Biros, Smriti M. Krishna, Susan K. Morton, Daniel J. Sexton, Jonathan Golledge   +5 more
doaj   +1 more source

Effects of Isometric Handgrip Training in Patients With Peripheral Artery Disease: A Randomized Controlled Trial [PDF]

, 2020
BackgroundMeta‐analyses have shown that isometric handgrip training (IHT) can reduce brachial systolic and diastolic blood pressure (BP) by >6/4 mm Hg, respectively.
Correia, Marilia A., Cucato, Gabriel, Farah, Breno Q., Green, Daniel J., Oliveira, Paulo L., Puech‐Leao, Pedro, Ritti‐Dias, Raphael M., Vianna, Lauro C., Wolosker, Nelson   +8 more
core   +2 more sources

A case–control comparison of acute-phase peripheral blood gene expression in participants diagnosed with minor ischaemic stroke or stroke mimics

Human Genomics, 2023
Background Past studies suggest that there are changes in peripheral blood cell gene expression in response to ischaemic stroke; however, the specific changes which occur during the acute phase are poorly characterised.
Joseph V. Moxon, Andrew Calcino, Ann-Katrin Kraeuter, James Phie, Georgina Anderson, Glenys Standley, Cindy Sealey, Rhondda E. Jones, Matt A. Field, Jonathan Golledge   +9 more
doaj   +1 more source

β-acetoxyisovaleryl alkannin (AAN-II) from Alkanna tinctoria promotes the healing of pressure-induced venous ulcers in a rabbit model through the activation of TGF-β/Smad3 signaling

Cellular & Molecular Biology Letters, 2021
Alkannin-based pharmaceutical formulations for improving wound healing have been on the market for several years. However, detailed molecular mechanisms of their action have yet to be elucidated.
Xiao Yang, Weijing Fan, Renyan Huang, Guobin Liu   +3 more
doaj   +1 more source