Results 11 to 20 of about 840,120 (301)

Meta-analysis of the association between angiotensin pathway inhibitors and COVID-19 severity and mortality

Systematic Reviews, 2021
Background Conflicting findings and the analysis of unpublished and retracted data have led to controversy on the safety of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in people with COVID-19 infection.
Malindu E. Fernando, Aaron Drovandi, Jonathan Golledge   +2 more
doaj   +1 more source

Author Correction: Effect of disease modifying anti-rheumatic drugs on major cardiovascular events: a meta-analysis of randomized controlled trials

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Shivshankar Thanigaimani, James Phie, Smriti Murali Krishna, Joseph Moxon, Jonathan Golledge   +4 more
doaj   +1 more source

Network Meta‐Analysis Comparing the Outcomes of Treatments for Intermittent Claudication Tested in Randomized Controlled Trials

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background No network meta‐analysis has considered the relative efficacy of cilostazol, home exercise therapy, supervised exercise therapy (SET), endovascular revascularization (ER), and ER plus SET (ER+SET) in improving maximum walking distance (MWD ...
Shivshankar Thanigaimani, James Phie, Chinmay Sharma, Shannon Wong, Muhammad Ibrahim, Pacific Huynh, Joseph Moxon, Rhondda Jones, Jonathan Golledge   +8 more
doaj   +1 more source

A meta-analysis of the efficacy of allopurinol in reducing the incidence of myocardial infarction following coronary artery bypass grafting

BMC Cardiovascular Disorders, 2018
Background The xanthine oxidase inhibitor allopurinol that is commonly used to treat gout, has been suggested to have pleiotropic effects that are likely to reduce the incidence of myocardial infarction (MI) in at risk individuals.
Tejas P. Singh, Tristan Skalina, Daniel Nour, Aarya Murali, Sean Morrison, Joseph V. Moxon, Jonathan Golledge   +6 more
doaj   +1 more source

Effect of disease modifying anti-rheumatic drugs on major cardiovascular events: a meta-analysis of randomized controlled trials

Scientific Reports, 2021
Disease modifying anti-rheumatic drugs (DMARDs) were developed to treat joint inflammation. There is growing evidence that anti-inflammatory drugs prevent major cardiovascular events (MACE).
Shivshankar Thanigaimani, James Phie, Smriti Krishna, Joseph Moxon, Jonathan Golledge   +4 more
doaj   +1 more source

Diabetes and peripheral vascular disease [PDF]

Journal of Vascular Surgery, 1999
Diabetes mellitus is found in as many as 13 million people nationally, or 5.2% of the US population, and more than 650,000 new cases are diagnosed annually.1 Clinical data that link diabetes to vascular disease are derived from several large epidemiologic studies.
Akbari, Cameron M., LoGerfo, Frank W.
openaire   +2 more sources

Pharmacological Targeting of the RAGE-NFκB Signalling Axis Impedes Monocyte Activation under Diabetic Conditions through the Repression of SHP-2 Tyrosine Phosphatase Function

Cells, 2023
Monocytes play a vital role in the development of cardiovascular diseases. Type 2 diabetes mellitus (T2DM) is a major CVD risk factor, and T2DM-induced aberrant activation and enhanced migration of monocytes is a vital pathomechanism that leads to ...
Marc Dorenkamp, Madina Nasiry, Dilvin Semo, Sybille Koch, Ivonne Löffler, Gunter Wolf, Holger Reinecke, Rinesh Godfrey   +7 more
doaj   +1 more source

The reproducibility of measuring maximum abdominal aortic aneurysm diameter from ultrasound images

The Ultrasound Journal, 2021
Background Accurate repeat assessment of the diameter of an abdominal aortic aneurysm (AAA) is important. This study investigated the reproducibility of different methods of measuring AAA diameter from ultrasound images.
Evan O. Matthews, Jenna Pinchbeck, Kylie Elmore, Rhondda E. Jones, Joseph V. Moxon, Jonathan Golledge   +5 more
doaj   +1 more source

Inositol in the MAnaGemENt of abdominal aortic aneurysm (IMAGEN): study protocol for a randomised controlled trial

Trials, 2017
Background An abdominal aortic aneurysm (AAA) is a focal dilation of the abdominal aorta and is associated with a risk of fatal rupture. Experimental studies suggest that myo-inositol may exert beneficial effects on AAAs through favourable changes to ...
Sophie E. Rowbotham, Jenna L. Pinchbeck, Georgina Anderson, Bernie Bourke, Michael Bourke, T. Christian Gasser, Rene Jaeggi, Jason S. Jenkins, Corey S. Moran, Susan K. Morton, Christopher M. Reid, Ramesh Velu, Lisan Yip, Joseph V. Moxon, Jonathan Golledge   +14 more
doaj   +1 more source

Cardiac allograft vasculopathy in a long-term follow-up after heart transplantation: Role of remnant cholesterol in residual inflammation

Cardiology Journal, 2022
BACKGROUND: Cardiac allograft vasculopathy (CAV) is a major prognosis limiting factor in heart transplantation (HTx). Disease development and progression are influenced by multiple determinants, but the role of remnant cholesterol (RC) in CAV has not yet
Emyal Alyaydin, Christian Pogoda, Angelo Dell`Aquila, Sven Martens, Izabela Tuleta, Holger Reinecke, Juergen R. Sindermann   +6 more
doaj   +1 more source