Results 61 to 70 of about 840,120 (301)

Effects of High Flavanol Dark Chocolate on Cardiovascular Function and Platelet Aggregation. [PDF]

, 2015
Regular consumption of chocolate and cocoa products has been linked to reduced cardiovascular mortality. This study compared the effects of high flavanol dark chocolate (HFDC; 1064mg flavanols/day for 6 weeks) and low flavanol dark chocolate (LFDC; 88mg ...
Akita, Armstrong, Atholl Johnston, Avolio, Balzer, Buijsse, Buijsse, Butcher, Curtis, Curtis, Custodis, David J. Collier, Duprez, Engler, Flammer, Flammer, Fredholm, Grassi, Grassi, Gresele, Gu, Gurvinder Rull, Heiss, Hermann, Holland, Holt, Innes, Janszky, Julian Shiel, Kokubo, Kris-Etherton, Kris-Etherton, Lakatta, Langer, Larsson, Larsson, Laurent, Lopez-Garcia, Manisty, Martina H. Lundberg, Murphy, Pereira, Rambaran, Rein, Ried, Roger Corder, Schroeter, Sever, Sharman, Smolenski, Taubert, Thorin, Timothy D. Warner, Varughese, Williams, Yu, Zetty N. Mohd-Zain   +56 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Opinions of vascular surgeons and podiatrists in Australia and New Zealand on the use of hyperbaric oxygen therapy for lower limb ulcers

BMJ Open Diabetes Research & Care, 2020
Introduction Hyperbaric oxygen therapy (HBOT) has been suggested to improve healing of lower limb ulcers, though the quality of available evidence is weak to moderate.
Jonathan Golledge, Aaron Drovandi, Malindu E Fernando, Tejas P Singh, Torres Woolley   +4 more
doaj   +1 more source

Cohort Study Examining the Association of Optimal Blood Pressure Control at Entry With Infrarenal Abdominal Aortic Aneurysm Growth

Frontiers in Cardiovascular Medicine, 2022
Background and AimThe benefit of controlling cardiovascular risk factors in slowing the progression of small abdominal aortic aneurysm (AAA) is controversial.
Diana Thomas Manapurathe, Joseph Vaughan Moxon, Joseph Vaughan Moxon, Smriti Murali Krishna, Smriti Murali Krishna, Frank Quigley, Michael Bourke, Michael Bourke, Bernard Bourke, Bernard Bourke, Rhondda E. Jones, Jonathan Golledge, Jonathan Golledge, Jonathan Golledge   +13 more
doaj   +1 more source

C-peptide: a predictor of cardiovascular mortality in subjects with established atherosclerotic disease [PDF]

, 2017
Aim: Insulin resistance and type 2 diabetes are independent risk factors for cardiovascular diseases. Levels of C-peptide are increased in these patients and its role in the atherosclerosis progression was studied in vitro and in vivo over the past ...
Ballanti, Marta, Cardellini, Marina, Cardolini, Iris, Davato, Francesca, Farcomeni, Alessio, Federici, Massimo, Grappasonni, Giulia, Guglielmi, Valeria, Ippoliti, Arnaldo, Menghini, Rossella, Morelli, Monica, Pecchioli, Chiara, Porzio, Ottavia, Rizza, Stefano   +13 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Systematic review and meta-analysis of mouse models of diabetes-associated ulcers

BMJ Open Diabetes Research & Care, 2020
Mouse models are frequently used to study diabetes-associated ulcers, however, whether these models accurately simulate impaired wound healing has not been thoroughly investigated.
Pacific Huynh, James Phie, Smriti Murali Krishna, Jonathan Golledge   +3 more
doaj   +1 more source

Barriers and enablers to walking in individuals with intermittent claudication: a systematic review to conceptualize a relevant and patient-centered program [PDF]

, 2018
Background: Walking limitation in patients with peripheral arterial disease (PAD) and intermittent claudication (IC) contributes to poorer disease outcomes.
Abaraogu, Ukachukwu, Brittenden, Julie, Dall, Philippa, Ezenwankwo, Elochukwu, Harwood, Amy, Seenan, Chris, Stuart, Wesley, Tew, Garry   +7 more
core   +5 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Coarctation of the aorta complicated with bilateral iliac artery dissection: A rare case

The Journal of Clinical Hypertension
The coarctation of the aorta (CoA) combined with heart defects or cerebral artery aneurysms is more prevalent in clinical practice. However, cases of concurrent bilateral iliac artery dissection (IAD) are extremely rare and have not been reported.
Wenye He, Yuhan Zhang, Luyao Wang, Hongsong Qin, Dawei Zhang, Qingzhi Hao   +5 more
doaj   +1 more source