Results 41 to 50 of about 251,516 (303)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Treatment of denture-related stomatitis improves endothelial function assessed by flow-mediated vascular dilation [PDF]

, 2016
Introduction: The presence of oral inflammation has recently been linked with the pathogenesis of cardiovascular diseases. While numerous studies have described links between periodontitis and endothelial dysfunction, little is known about the influence ...
Czesnikiewicz-Guzik, Marta, Dembowska, Elżbieta, Guzik, Tomasz, Loster, Jolanta, Maciąg, Anna, Maciąg, Joanna, Nowakowski, Daniel, Osmenda, Grzegorz, Robertson, Douglas, Wilk, Grzegorz   +9 more
core   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Endovascular single-branched stent graft to treat complicated type B aortic dissection involving aortic arch anomalies

European Journal of Medical Research
Background The optimal treatment of complicated type B aortic dissection (cTBAD) involving arch anomalies remain unclear. Methods We consecutively enrolled patients with cTBAD involving arch anomalies who underwent endovascular repair using a single ...
Mengyang Kang, Hao Qin, Yan Meng, Qiang Ma, Junbo Zhang, Hongyan Tian   +5 more
doaj   +1 more source

Prognostic value and immunomodulatory role of DNM1L in gastric adenocarcinoma

Frontiers in Oncology
BackgroundMitochondrial fusion and fission are critical for the morphology and function of cells. DNM1L encodes dynamin-related protein 1 (DRP1), a key protein mediating mitochondrial fission, which is upregulated in a variety of cancers and is strongly ...
Zhuo Zhao, Lingxia Li, Yan Liu, Lei Shi, Meijie Yuan, Hongshuo Shi, Qing Ji, Guobin Liu, Jian Sun   +8 more
doaj   +1 more source

Gene Therapy for Cardiovascular Disease [PDF]

, 2003
The last decade has seen substantial advances in the development of gene therapy strategies and vector technology for the treatment of a diverse number of diseases, with a view to translating the successes observed in animal models into the clinic ...
Baker, Andrew H., Denby, Laura, Dishart, Kate L., Work, Lorraine M.   +3 more
core   +4 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Impact of inferior vena cava thrombosis on the prevalence of pulmonary embolism in patients with lower extremity deep vein thrombosis

Scientific Reports
Inferior vena cava thrombosis (IVCT) is a special form of venous thromboembolism. Lower extremity deep vein thrombosis (LEDVT) is associated with an increased incidence of pulmonary embolism (PE), but the association between concomitant IVCT and PE in ...
Yiman Zhang, Yan Meng, You Li, Mengyang Kang, Qiang Ma, Junbo Zhang, Jian Yang, Hongyan Tian, Qian Yin   +8 more
doaj   +1 more source

LncRNA BCYRN1/miR-490-3p/POU3F2, served as a ceRNA network, is connected with worse survival rate of hepatocellular carcinoma patients and promotes tumor cell growth and metastasis

Cancer Cell International, 2020
s Backgrounds LncRNA Brain Cytoplasmic RNA 1 (BCYRN1) has been certified to modulate cancer cells growth and aggressiveness in several tumors. However, research about function of BCYRN1 in hepatocellular carcinoma (HCC) is limited.
Shichao Ding, Yanfeng Jin, Qingzhi Hao, Yanmeng Kang, Ruiping Ma   +4 more
doaj   +1 more source

Transradial peripheral vascular intervention using Fowler’s position and Terumo R2P system for patients with heart failure: two case reports

Journal of Medical Case Reports, 2022
Background Positioning a patient on the catheterization table is important for proper cardiac or respiratory function during peripheral vascular interventions.
Akihiro Nakamura, Kenjiro Sato, Hideaki Endo   +2 more
doaj   +1 more source