Results 141 to 150 of about 16,374 (303)

Evaluating the effects of a hospital utilisation improvement program on platelet transfusions: A pre‐post study

Transfusion Medicine, EarlyView.
Abstract Background Annually millions of platelet concentrate (PC) are transfused worldwide. The decision regarding PC transfusion is often complex; therefore, the implementation of a hospital programme designed to streamline and facilitate the decision‐making process is beneficial. Such a programme helps standardise transfusion practices, ensures that
Piotr F. Czempik, Jakub Rudzki, Michał Porada   +2 more
wiley   +1 more source

Microcirculatory perfusion is improved with plasma, but not with crystalloids, in a rat polytraumatic shock model

Transfusion, EarlyView.
Abstract Background Traumatic shock is associated with microcirculatory dysfunction. Plasma resuscitation for traumatic shock outside the context of bleeding may exert benefit by augmenting intravascular volume and inhibiting endotheliopathy. However, its effects on microcirculatory perfusion and tissue oxygenation in trauma remain poorly understood ...
Tarık Gözden, Bulent Ergin, Can Ince, Nicole P. Juffermans   +3 more
wiley   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source

Influence of low‐dose dopamine on exercise in fibrosing interstitial lung disease

Experimental Physiology, EarlyView.
ABSTRACT Fibrotic interstitial lung disease (FILD) is associated with dyspnoea and exercise intolerance. In other cardiorespiratory conditions, heightened carotid body (CB) chemoreflex sensitivity is associated with reduced exercise capacity. We tested the hypothesis that CB chemoreflex inhibition would improve exercise endurance time (EET) and reduce ...
Charlotte Chen, Jui‐Lin Fan, Michael Plunkett, Thalia Babbage, John Kolbe, Julian F. R. Paton, James P. Fisher   +6 more
wiley   +1 more source

Passive heat therapy is feasible but does not affect cardiometabolic health outcomes in persons with spinal cord injury – a pilot study

Experimental Physiology, EarlyView.
Abstract Passive heat therapy can improve cardiometabolic health outcomes in some clinical populations, making it a potential therapeutic tool for individuals with spinal cord injury (SCI), who exhibit elevated cardiometabolic disease risk and face barriers to physical activity.
Sven P. Hoekstra, Christof A. Leicht, Dean Kellogg Jr., Yubo Wu, Terry Romo, Hannah Uhlig‐Reche, Michelle Trbovich   +6 more
wiley   +1 more source

Surgical repair of peripherally inserted central catheter extravasation via a transmanubrial approach. [PDF]

J Vasc Surg Cases Innov Tech
Bungo M, Uemura H, Nakamura A, Sakaguchi T.   +3 more
europepmc   +1 more source

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

Experimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts, Lydia L. Simpson, Jack S. Talbot, Elliott J. Jenkins, Travis D. Gibbons, Connor A. Howe, Lauren E. Maier, Emily R. Vanden Berg, Alex M. Williams, Philip N. Ainslie, Samuel J. Oliver, Craig D. Steinback, Mike Stembridge, Jonathan P. Moore   +13 more
wiley   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

The Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark, Eric Rytkin, Andrei Alexandru Mircea, Igor R. Efimov   +3 more
wiley   +1 more source

Implementation of a peripherally inserted central catheter service by pediatric anesthesiologists and anesthesia assistants. [PDF]

Can J Respir Ther
Kiberd MB, Comeau JL, Jreige S, MacInnis M, Dumbarton T.   +4 more
europepmc   +1 more source