Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
An entrepreneurial countryside?
Architecture and urban design are central selling points in globalized models of urban development, advocated by city strategies to boost competitiveness.
Heini-Emilia Saari
doaj
Analyzing urban sprawl and urbanisation dynamics: A case study of Bejaia, Oued-Ghir, and Tala-Hamza [PDF]
Understanding urban sprawl is crucial as it provides a dynamic perspective on urban areas, revealing the driving forces and explanatory factors behind their expansion.
Tebbane Bouktit Kaouther +2 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
MODERN GEODEMOGRAPHIC SITUATION IN PERIPHERAL RURAL AREAS IN THE SOUTH OF EUROPEAN RUSSIA
The demographic situation in Russia, despite the measures taken, largely retains negative. Low fertility combined with high mortality led to the depopulation effect resulting in natural population decline in many regions of the country, which can not ...
Natalia Aleksandrovna Shchitova +1 more
doaj
Lambadão: breaking the borders of the periphery [PDF]
Lidiane Freitas de Barros +2 more
openalex +1 more source
Paramagnetic Reentrance Effect in NS Proximity Cylinders
A scenario for the unusual paramagnetic reentrance behavior at ultra-low temperatures in Nb-Ag, Nb-Au, and Nb-Cu cylinders is presented. For the diamagnetic response down to temperatures of the order 15 mK, the standard theory (quasi-classical ...
Belzig +13 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Remote AI Supported E-Multidisciplinary Oncology Conference in Breast Cancer as a Technology and Method to Optimize Outcomes in the Peripheries [PDF]
Constantinos S. Mammas +3 more
openalex +1 more source
Brand Agriculture and Economic Geography: A General Equilibrium Analysis [PDF]
This paper presents a general equilibrium model of NEG incorporating the brand agriculture which produces differentiated agricultural products. Focusing on the core-periphery space, we show that highly differentiated brand agriculture can be sustained in
Masahisa Fujita, Nobuaki Hamaguchi
core

