Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter +5 more
wiley +1 more source
Contrast-Enhanced Ultrasound Combined With Biopsy for the Preoperative Diagnosis of a Rare Pelvic Schwannoma: A Case Report. [PDF]
Am J Case RepWang J, Wei L, Wang Y.
europepmc +1 more source
Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo +11 more
wiley +1 more source
Internal lysis of contracted clots is accelerated by fiber alignment and bundling. [PDF]
J Thromb HaemostRisman RA +9 more
europepmc +1 more source
Arthritis Care &Research, EarlyView.Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Social Representations of Healthcare Organisational Models and Professional Practice Among Public-Sector Physicians and Nurses in Portugal: A Prototypical Analysis. [PDF]
Healthcare (Basel)Fernandes A, Santinha G, Forte T.
europepmc +1 more source
Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis
Arthritis Care &Research, EarlyView.Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich +35 more
wiley +1 more source
Shear Stress-Stimulated Trafficking of Endothelial Piezo1 to Splenic Capsule Boosts Spleen Contraction and Exercise Endurance. [PDF]
J Extracell VesiclesLou J +12 more
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla +8 more
wiley +1 more source
Nucleolar reorganization on stress depends on physicochemical changes due to reduced nascent rRNA synthesis. [PDF]
EMBO RepGhosh S, Sen S, Mazumder A.
europepmc +1 more source