Results 51 to 60 of about 49,443 (234)

In vivo reduction of biofilm seeded on orthopaedic implants: safety and efficacy of portable electromagnetic induction heating

open access: yesBone & Joint Research
Aims: Electromagnetic induction heating has demonstrated in vitro antibacterial efficacy over biofilms on metallic biomaterials, although no in vivo studies have been published.
Enrique Cordero García-Galán   +7 more
doaj   +1 more source

Outcomes of total hip and knee arthroplasty in special populations: a synopsis and critical appraisal of systematic reviews

open access: yesArthroplasty, 2023
Introduction This study aimed to present and critically appraise the best available evidence investigating associations between some pre-defined patient-related characteristics and perioperative complications or other outcomes in THA and TKA.
Dimitris Challoumas   +8 more
doaj   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

open access: yesAdvanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan   +3 more
wiley   +1 more source

Open reduction and internal fixation offers lower hip‐related complications compared to stem revision in Vancouver B2 fractures around cemented polished tapered femoral stems

open access: yesJournal of Experimental Orthopaedics
Purpose Periprosthetic femoral fractures (PFFs) after total hip arthroplasty (THA) are increasing, particularly Vancouver B2 fractures around cemented polished tapered femoral stems. Open reduction and internal fixation (ORIF) are more frequently used in
Olof Sköldenberg   +4 more
doaj   +1 more source

Denosumab might prevent periprosthetic bone loss after total hip and knee arthroplasties: a review

open access: yesArthroplasty, 2021
Total hip arthroplasty and total knee arthroplasty are extensively used for the treatment of the end-stage degenerative joint diseases. Currently, periprosthetic bone loss is still the major cause of aseptic loosening, resulting in implant failures ...
Jianda Xu   +9 more
doaj   +1 more source

Infection in prosthetic material [PDF]

open access: yes, 2015
Surgical site infection (SSI) occurs when a wound created as part of a surgical procedure becomes infected. SSI is one of the most common healthcare-associated infections and occurs in approximately 5% of patients undergoing a surgical procedure. SSI may
Chetter, Ian, Smith, George
core   +1 more source

Harnessing chimeric antigen receptor macrophages against solid tumors

open access: yesCancer Communications, EarlyView.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang   +3 more
wiley   +1 more source

Haversian canal structures can be associated with size effects in cortical bone [PDF]

open access: yes, 2012
Prediction of periprosthetic failure may be improved by an improved model of bone elasticity which includes microstructural information. Micropolar theory facilitates such information to be included in a continuum model.
Frame, Jamie Campbell   +2 more
core  

Antibacterial surface modification of titanium implants in orthopaedics [PDF]

open access: yes, 2018
The use of biomaterials in orthopaedics for joint replacement, fracture healing and bone regeneration is a rapidly expanding field. Infection of these biomaterials is a major healthcare burden, leading to significant morbidity and mortality. Furthermore,
Damiati, Laila   +3 more
core   +1 more source

Laser Disinfection Acts as Biofilm‐Disrupter in Periprosthetic Joint Infection (PJI)

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT Infections after joint arthroplasties represent a devastating and progressively escalating complication with increased morbidity and mortality. The eradication of biofilms from infected implants is still an unsolved challenge. The erbium‐doped yttrium aluminum garnet (Er:YAG) laser, which delivers high‐energy light for rapid tissue ablation ...
Lukas K. Kriechbaumer   +11 more
wiley   +1 more source

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