Results 51 to 60 of about 50,458 (278)

Effectiveness of circular external fixator in periprosthetic fractures around the knee

BMC Musculoskeletal Disorders, 2020
Background The incidence of periprosthetic fractures after total joint arthroplasty (TJA) is rising due to an increasing number of TJAs performed annually and the growing elderly population.
Koji Nozaka, Naohisa Miyakoshi, Michio Hongo, Yuji Kasukawa, Hidetomo Saito, Hiroaki Kijima, Hiroyuki Tsuchie, Motoki Mita, Yoichi Shimada   +8 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

In vivo reduction of biofilm seeded on orthopaedic implants: safety and efficacy of portable electromagnetic induction heating

Bone & Joint Research
Aims: Electromagnetic induction heating has demonstrated in vitro antibacterial efficacy over biofilms on metallic biomaterials, although no in vivo studies have been published.
Enrique Cordero García-Galán, Marina Medel-Plaza, José J. Pozo-Kreilinger, Héctor Sarnago, Óscar Lucía, Alicia Rico-Nieto, Jaime Esteban, Enrique Gomez-Barrena   +7 more
doaj   +1 more source

Infection in prosthetic material [PDF]

, 2015
Surgical site infection (SSI) occurs when a wound created as part of a surgical procedure becomes infected. SSI is one of the most common healthcare-associated infections and occurs in approximately 5% of patients undergoing a surgical procedure. SSI may
Chetter, Ian, Smith, George
core   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Outcomes of total hip and knee arthroplasty in special populations: a synopsis and critical appraisal of systematic reviews

Arthroplasty, 2023
Introduction This study aimed to present and critically appraise the best available evidence investigating associations between some pre-defined patient-related characteristics and perioperative complications or other outcomes in THA and TKA.
Dimitris Challoumas, David Munn, Henrietta Stockdale, Nigel Ng, Michael McCormick, Tareq Altell, Shaheer Joiya, James Horton, Bryn Jones   +8 more
doaj   +1 more source

A systematic review of the evidence for single stage and two stage revision of infected knee replacement [PDF]

, 2013
BACKGROUND: Periprosthetic infection about the knee is a devastating complication that may affect between 1% and 5% of knee replacement. With over 79 000 knee replacements being implanted each year in the UK, periprosthetic infection (PJI) is set to ...
A Beswick, A Ocguder, A Trampuz, AA Haleem, AA Hofmann, AG Rosenberg, AH Wilde, AJ Johnson, Andrew P Sprowson, AT Rasul Jr, BD Springer, CJ Wang, CL Romano, CM Jhao, CR Gooding, DJ Jaekel, DT Tsukayama, E Jamsen, FF Buechel, FS Haddad, G Von Foerster, GA Macheras, GC Babis, GH Westrich, GS Van Thiel, H Husted, H Lu, H Segawa, H-R Choi, H-T Huang, Health Protection Agency, Helen Parsons, I Byren, IS Vanhegan, J Cordero-Ampuero, J Gardner, J Lopez-Contreras, J Parvizi, J Parvizi, J Singer, J Tanner, JA Anderson, JABR Rand, James PM Masters, JH Lonner, JK Lee, JM Cuckler, JN Insall, K Hirakawa, KO Oduwole, LA Whiteside, LS Borden, M Silva, M Villanueva-Martinez, MA Mont, MAR Freeman, MC MacAvoy, MF Kurd, MG Freeman, MG Wilson, MH Henderson Jr, Mike Reed, Nicholas A Smith, NV Kalore, P Baker, P Dixon, Pedro Foguet, R Ferrari, RH Walker, RL Barrack, RMD Meek, RP Evans, RP Pitto, RT Goldman, RW Parkinson, S Bengtson, S Gulhane, S Kohl, S-J Park, SB Goksan, SJ Volin, SM Durbhakula, SM Kurtz, SMJ Mortazavi, T Bauer, T Mahmud, TK Fehring, TWB Kim, V Pascale, WJ Bose, WJ Hart, WO Jackson, Y-P Su, YC Hsu, Z Wan   +94 more
core   +1 more source

Corrosion in Modular Revision Hip Stem Tapers – A Retrieval Analysis

Journal of Orthopaedic Research, EarlyView.
ABSTRACT In revision hip arthroplasty, modular stems enable intraoperative adjustment of the biomechanics of the hip to ensure a stable joint function even in complex anatomical cases. Modular stem junctions, however, carry the risk of junction degradation due to corrosive processes or even junction breakage.
Therese Bormann, Haolan Yan, Sebastian Jaeger, Mareike Schonhoff, J. Philippe Kretzer   +4 more
wiley   +1 more source

Denosumab might prevent periprosthetic bone loss after total hip and knee arthroplasties: a review

Arthroplasty, 2021
Total hip arthroplasty and total knee arthroplasty are extensively used for the treatment of the end-stage degenerative joint diseases. Currently, periprosthetic bone loss is still the major cause of aseptic loosening, resulting in implant failures ...
Jianda Xu, Huan Li, Yuxing Qu, Chong Zheng, Bin Wang, Pengfei Shen, Zikang Xie, Kang Wei, Yan Wang, Jianning Zhao   +9 more
doaj   +1 more source

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon, Victoria R. Wong, Samuelson E. Osifo, Timothy Edwards, Himanshu Rao, Jewelia Rempuszewski, Andrew J. Frear, Shaan Sadhwani, Neel B. Shah, Kenneth L. Urish   +9 more
wiley   +1 more source