Results 41 to 50 of about 12,374 (221)

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

Periprosthetic fractures around the knee:current concepts and advances in management [PDF]

, 2014
Knee replacement is an effective treatment for pain and functional impairment secondary to degenerative joint conditions. The number of knee replacements performed continues to rise.
Mehendale, Sanchit, Whitehouse, Michael R   +1 more
core   +1 more source

Periprosthetic joint infection risk is comparable between unicompartmental knee arthroplasty to total knee arthroplasty conversion and primary total knee arthroplasty: A systematic review and meta‐analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Unicompartmental knee arthroplasty (UKA) offers benefits over total knee arthroplasty (TKA), but some studies indicated higher revision rates, often involving conversion to TKA. The infection risk associated with UKA to TKA conversion compared to primary TKA is not definitively established.
Maximilian Budin, Matthew De Ruyter, Zachary Christopher Lum, Jürgen Slapar, Jochen Gerhard Hofstaetter, Georg Hauer, Andreas Leithner, Patrick Sadoghi   +7 more
wiley   +1 more source

Patients with previous anterior cruciate ligament reconstruction achieve equally good outcomes after total knee arthroplasty: A Swedish registry‐based study of 7755 patients

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Patients who have undergone anterior cruciate ligament reconstruction (ACLR) may later require total knee arthroplasty (TKA) due to osteoarthritis (OA). The impact of previous ACLR on patient‐reported outcomes (PROs) after TKA remains uncertain.
Ioannis Syrikas, Ioannis Karikis, Neel Desai, Georgios Tsikandylakis   +3 more
wiley   +1 more source

Compress Periprosthetic Fractures: Interface Stability and Ease of Revision [PDF]

, 2009
Periprosthetic fractures after massive endoprosthetic reconstructions pose a reconstructive challenge and jeopardize limb preservation. Compressive osseointegration technology offers the promise of relative ease of prosthetic revision, since fixation is ...
O’Donnell, Richard J., Healey, John H., Tyler, Wakenda K., Boland, Patrick J., Morris, Carol D.   +4 more
core   +1 more source

Synovial interleukin‐6 point‐of‐care testing, alone and combined with D‐dimer, supports rapid diagnosis of periprosthetic joint infection

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Data on the reliability of point‐of‐care (POC) tests for the rapid diagnosis of periprosthetic joint infections (PJI) using synovial fluid (SF) D‐dimer (DD), interleukin 6 (IL‐6) and procalcitonin (PCT) are limited. This study aimed to address this issue by evaluating the diagnostic accuracy of POC tests for SF DD, IL‐6 and PCT in ...
Sujeesh Sebastian, Hibah Abdulwahab Abusulaiman, Veronika Achatz, Matteo Spadini, Tobias Josef Niedrist, Markus Herrmann, Jochen Gerhard Hofstaetter   +6 more
wiley   +1 more source

Periprosthetic fracture management of the proximal femur

OTA International, 2023
Summary:. The most common periprosthetic fractures occur around the hip. The most widely used classification is the Vancouver classification, and management requires careful planning and skill in both arthroplasty and fracture surgery.
Luis G. Padilla-Rojas, MD, Dario E. Garín-Zertuche, MD, Leonardo López-Almejo, MD, Germán Garabano, MD, César Ángel Pesciallo, MD, Jaime A. Leal, MD, Andrés Pinzón, MD, Vincenzo Giordano, MD, Robinson Esteves-Pires, MD   +8 more
doaj   +1 more source

Extracortical plate fixation with new plate inserts and cerclage wires for the treatment of periprosthetic hip fractures [PDF]

, 2014
PURPOSE Fixation of periprosthetic hip fractures with intracortical anchorage might not be feasible in cases with bulky implants and/or poor bone stock.
Bigolin, Gianni, Nötzli, Hubert P, Zumstein, Matthias, Bastian, Johannes Dominik, Butscher, Andre   +4 more
core   +1 more source

Revision Total Hip Arthroplasty + Stabilisation with Stainless Steel Wires for Periprosthetic Fractures

Journal of Clinical and Biomedical Sciences
Total hip arthroplasty (THA) offers a considerable problem in managing periprosthetic fractures surrounding the femoral stem, and the best course of treatment is still debatable.
Jayakrishnan Aryadev, Hariprasad S, Arun H S, Madhavan P   +3 more
doaj   +1 more source

Conservative treatment of periprosthetic femur fractures around metaphyseal short stems – A feasible option?

Trauma Case Reports, 2017
Periprosthetic femoral fractures are rare but significant events following total hip replacement. Metaphyseal short stems have recently been popularized as a bone preserving alternative to conventional uncemented total hip replacement.
K. Toth, H. Gality, K. Gion, K. Sisak
doaj   +1 more source