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Understanding Periprosthetic Joint Infection

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Periprosthetic Joint Infection

JBJS Reviews, 2020
Total joint arthroplasty (TJA), the implantation of an artificial joint replacement, has become a relatively commonly practiced operation in many parts of the world. The most common reasons for performing a TJA are to restore mobility and alleviate symptoms of osteoarthritis, and reconstruction after fracture.
Aron Keshishian, Andrew Foster, Georg Matziolis, T. Fintan Moriarty, Henk Eijer   +4 more
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Periprosthetic joint infection

The Lancet, 2016
Periprosthetic joint infections are a devastating complication after arthroplasty and are associated with substantial patient morbidity. More than 25% of revisions are attributed to these infections, which are expected to increase. The increased prevalence of obesity, diabetes, and other comorbidities are some of the reasons for this increase ...
Bhaveen H, Kapadia, Richard A, Berg, Jacqueline A, Daley, Jan, Fritz, Anil, Bhave, Michael A, Mont   +5 more
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Diagnosis of Periprosthetic Joint Infection

The Journal of Arthroplasty, 2014
Diagnosis of periprosthetic joint infection (PJI), one of the major causes of failure of total joint arthroplasty, continues to pose a challenge. One of the major reasons is the lack of a ''gold standard'' to distinguish between septic and aseptic failure.
B. Zmistowski, C. Della Valle, T. W. Bauer, K. N. Malizos, A. Alavi, H. Bedair, R. E. Booth, P. Choong, C. Deirmengian, G. D. Ehrlich, A. Gambir, R. Huang, Y. Kissin, H. Kobayashi, N. Kobayashi, V. Krenn, L. Drago, D. Lorenzo, S. B. Marston, G. Meermans, J. Perez, J. J. Ploegmakers, A. Rosenberg, C. Simpendorfer, P. Thomas, S. Tohtz, J. A. Villafuerte, P. Wahl, F. Wagenaar, E. Witzo   +29 more
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Periprosthetic joint infection

The Bone & Joint Journal, 2015
The number of publications in the literature related to periprosthetic joint infection (PJI) has risen 100 fold during the last decade. This confirms the fact that this is a dreaded complication in the minds of the medical community.
J, Parvizi, F S, Haddad
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Periprosthetic Joint Infection

New England Journal of Medicine, 2023
Javad, Parvizi, Michael G, Schmidt, Ellie J C, Goldstein   +2 more
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Periprosthetic Joint Infection: Treatment Options

Orthopedics, 2010
Periprosthetic joint infection has become the most common cause of failure following total knee arthroplasty. Over the past 4 decades, treatment of this disease has evolved with technological innovations and pathogen profiling. The appropriate treatment selection is dependent on patient immune system quality, timing of symptom onset, and pathogen type.
Javad, Parvizi, Benjamin, Zmistowski, Bahar, Adeli   +2 more
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Diagnosis of Periprosthetic Joint Infections

HIP International, 2012
Advances in implant design, surgical technique, peri-operative antimicrobial prophylaxis and laminar airflow operating room environment have made total joint arthroplasty one of the most successful surgical procedures of all times. Orthopaedic implants, however, remain prone to microbial contamination resulting in persistent risk of implant-associated
Olivier, Borens, Stéphane, Corvec, Andrej, Trampuz   +2 more
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Culture-Negative Periprosthetic Joint Infection

Journal of Bone and Joint Surgery, 2014
➤ Negative results on culture still pose a real challenge in the diagnosis of periprosthetic joint infection.➤ There are numerous reasons for the inability to isolate the infecting organism from the affected joint, the most important of which is the administration of antibiotics prior to obtaining culture samples.➤ For patients suspected of having a ...
Javad, Parvizi, Omer Faruk, Erkocak, Craig J, Della Valle   +2 more
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