Results 21 to 30 of about 89,334 (279)

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection. [PDF]

open access: yesJ Orthop Res
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Shannon MF   +9 more
europepmc   +2 more sources

Nano wear particles and the periprosthetic microenvironment in aseptic loosening induced osteolysis following joint arthroplasty

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Joint arthroplasty is an option for end-stage septic arthritis due to joint infection after effective control of infection. However, complications such as osteolysis and aseptic loosening can arise afterwards due to wear and tear caused by high joint ...
Yu Xie   +11 more
doaj   +1 more source

Periprosthetic joint infection and immunity: Current understanding of host–microbe interplay

open access: yesJournal of Orthopaedic Research, 2023
Periprosthetic joint infection (PJI) is a major complication of total joint arthroplasty. Even with current treatments, failure rates are unacceptably high with a 5‐year mortality rate of 26%.
N. Piuzzi   +5 more
semanticscholar   +1 more source

Combined bone scintigraphy with 99mTc-MDP and 99mTc-ciprofloxacin in differentiation of hip and knee prosthesis aseptic loosening and infection: A preliminary study [PDF]

open access: yesVojnosanitetski Pregled, 2017
Background/Aim. Although the number of new primary implantation of hip and knee prostheses every year increases, the rate of failed arthroplasty is nearly the same.
Pucar Dragan   +9 more
doaj   +1 more source

Periprosthetic Joint Infection Diagnosis: A Narrative Review

open access: yesAntibiotics, 2023
Replacement of native joints aims to restore patients’ quality of life by relieving pain and improving joint function. While periprosthetic joint infection (PJI) affects a small percentage of patients, with an estimated incidence of 1–9% following ...
Konstantinos Tsikopoulos, G. Meroni
semanticscholar   +1 more source

Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023

open access: yesAntibiotics, 2023
Periprosthetic joint infection (PJI) is a rare yet devastating complication following total joint arthroplasty (TJA). Early and accurate diagnosis of PJI is paramount in order to maximize the chances of successful treatment.
M. Yilmaz   +4 more
semanticscholar   +1 more source

Promising applications of D-amino acids in periprosthetic joint infection

open access: yesBone Research, 2023
Due to the rise in our aging population, a disproportionate demand for total joint arthroplasty (TJA) in the elderly is forecast. Periprosthetic joint infection (PJI) represents one of the most challenging complications that can occur following TJA, and ...
M. Caldwell   +6 more
semanticscholar   +1 more source

Profiling the Immune Response to Periprosthetic Joint Infection and Non-Infectious Arthroplasty Failure

open access: yesAntibiotics, 2023
Arthroplasty failure is a major complication of joint replacement surgery. It can be caused by periprosthetic joint infection (PJI) or non-infectious etiologies, and often requires surgical intervention and (in select scenarios) resection and ...
Cody R. Fisher, Robin Patel
semanticscholar   +1 more source

Enough is enough: salvage procedures in severe periprosthetic joint infection

open access: yesArthroplasty, 2023
In severe cases of periprosthetic joint infection involving negative host-dependent factors, individual-based decisions between a curative therapy vs. salvage procedure are necessary.
Y. Gramlich, J. Parvizi
semanticscholar   +1 more source

Periprosthetic joint infection increases the risk of one-year mortality. [PDF]

open access: yes, 2013
BACKGROUND: Periprosthetic joint infection continues to potentially complicate an otherwise successful joint replacement. The treatment of this infection often requires multiple surgical procedures associated with increased complications and morbidity ...
Casper, MD, David S   +4 more
core   +2 more sources

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