Results 81 to 90 of about 16,124 (189)

Is It Safe to Implant Prosthesis When Frozen Section Reports Positive During Joint Arthroplasty? A Retrospective Cohort Study

Orthopaedic Surgery, EarlyView.
This study demonstrated that it is improper to overinterpret isolated frozen section positivity. It may be safe to implant prosthesis in patients who had positive frozen sections but without other signs of infection. Surgeons opting for staged revisions solely based on neutrophil counts risk unnecessary morbidity, particularly in patients with ...
Chiyuan Ma, Pingan Lin, Lingyun Wu, Jieli Zhou, Jiaxuan Zou, Pengfei Hu, Lidong Wu, Haobo Wu   +7 more
wiley   +1 more source

TREATMENT OF DEEP PERIPROSTHETIC INFECTION OF KNEE JOINT

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
In connection with the increase in arthroplasty of joints, the problem of infectious complications becomes topical. The aim of the study was to increase the effectiveness of purulent complications treatment after total knee arthroplasty. Material and
Ivantsov V. A., Lashkovsky V. V., Bogdanovich I. P., Lazarevich S. N.   +3 more
doaj   +1 more source

Metformin Use Is Associated With Reduced Inflammation and Pain After Total Knee Arthroplasty in Patients With Type 2 Diabetes

Orthopaedic Surgery, EarlyView.
Long‐term metformin use in T2DM patients undergoing TKA significantly reduced postoperative inflammation and pain. On postoperative day 3, CRP, IL‐6, ESR, D‐dimer levels and VAS scores were markedly lower in the metformin group, suggesting potential perioperative anti‐inflammatory and analgesic benefits.
Zhongyu Luo, Xiaoying Zhong, Chen Zhang, Mingwei Hu, Muyang Yu, Bin Feng, Xisheng Weng   +6 more
wiley   +1 more source

Periprosthetic Joint Infection (PJI).

The archives of bone and joint surgery
Periprosthetic joint infection (PJI) is a serious complication that can occur after joint arthroplasty, significantly affecting both the healthcare system and patients due to high costs and mortality rates. Managing PJI is complex and presents significant challenges in orthopedic surgery because there is no standardized definition for PJI and no ...
Kalali, Naeemeh, Ebrahimzadeh, Mohammad H., Moradi, Ali, Jirofti, Nafiseh   +3 more
openaire   +2 more sources

Long‐Term Results of Anatomic Stemless Shoulder Prosthesis in Patients With Primary Osteoarthritis

Orthopaedic Surgery, EarlyView.
Stemless anatomic shoulder prostheses demonstrate sustained improvements in function and range of motion, with high patient satisfaction and low revision rates, even after exceptionally long follow‐up. Outcomes are comparable to other stemless designs, supporting their long‐term effectiveness in primary osteoarthritis.
Kevin Knappe, Franziska Becker, Raphael Trefzer, Mustafa Hariri, Anna‐Katharina Nolte, Matthias Bülhoff   +5 more
wiley   +1 more source

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

Relationship between vitamin D deficiency and early implant failure and osseointegration

Periodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron, Nathan E. Estrin, Ana Paz, Reinhard Gruber, Nima Farshidfar, Yufeng Zhang, Anton Sculean, Thomas G. Wiedemann, Paras Ahmad   +8 more
wiley   +1 more source

Corrosion Damage in Retrieved CoCrMo/Ti‐6Al‐4V Modular Junctions in Femoral Revision Total Knee Components

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 6, June 2026.
ABSTRACT Modularity in revision total knee arthroplasty (TKA) is prevalent; however, corrosion mechanisms at modular junctions in these devices are not well investigated compared to total hip arthroplasty (THA). This retrieval study analyzed corrosion damage on modular junctions of cobalt chromium molybdenum (CoCrMo) alloy femoral components with a ...
Hwaran Lee, Michael A. Kurtz, Emma Barnes, Gregg R. Klein, Steven M. Kurtz, Jeremy L. Gilbert   +5 more
wiley   +1 more source

Spinal Implant–Associated Infection in Type 2 and Type 1 Diabetes: Phenotype‐Specific Inflammatory Features and Therapeutic Response to Semaglutide

JOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Background Diabetes mellitus (DM) is a major risk factor for postoperative infection and wound complications in spine surgery, yet distinctions between Type 2 (T2DM) and Type 1 (T1DM) pathophysiology are rarely addressed. This study compares infectious burden, wound healing, and immune response among a murine model of spinal implant‐associated
Thomas E. Olson, Trevor S. Lloyd, Christopher D. Hamad, Rene F. Chun, Joshua Wiener, Autreen Golzar, Joshua Mehany, Soroush Shahamatdar, Andrew Kittredge, Lauren Pearce, Kevin P. Francis, Farres Obeidin, Langston T. Holly, Michael R. Yeaman, John S. Adams, Nicholas M. Bernthal, William L. Sheppard   +16 more
wiley   +1 more source

Host–Pathogen Dual Targeting With Repurposed Drugs Identifies a Synergistic Therapy for Intracellular Staphylococcus aureus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
A large intracellular drug‐repurposing screen identifies a potent synergy between 5‐fluoro‐2′‐deoxycytidine and rifapentine, acting through dual host–pathogen targeting to reduce Staphylococcus aureus burdens across strains, cell types, and infection models (created with BioRender).
Blanca Lorente‐Torres, Helena Á. Ferrero, Pablo Castañera, Jesús Llano‐Verdeja, Sergio Fernández‐Martínez, Amanda Herrero‐González, Farzaneh Javadimarand, Roberto López, Jesús F. Aparicio, Andrew M. Edwards, Volker Behrends, Luis M. Mateos, Álvaro Mourenza, Michal Letek   +13 more
wiley   +1 more source