Results 91 to 100 of about 9,720 (205)

Capacity of perirhinal cortex network for recognising frequently repeating stimuli [PDF]

, 2002
Much evidence indicates that discrimination of the familiarity of visual stimuli is dependent on the perirhinal cortex of the temporal lobe. A stimulus can become familiar to animals or humans either when a stimulus is seen once but is behaviourally ...
Malcolm W. Brown, Brown, MW, Bogacz, Rafal, Bogacz, R, Rafal Bogacz   +4 more
core   +1 more source

A Scoping Review of Non‐Opioid Therapeutics for Opioid Withdrawal: Translational Relevance to Neonatal Opioid Withdrawal Syndrome (NOWS) Research

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT In the wake of the ongoing opioid epidemic, the incidence of neonatal opioid withdrawal syndrome (NOWS) has surged. While the short‐term effects of NOWS are well‐characterized, long‐term physiological and molecular consequences remain unclear.
Sara L. Mills‐Huffnagle, Oliver M. Lowden, Rhea E. Sullivan, Taryn E. McFadden, Jennifer E. Nyland   +4 more
wiley   +1 more source

Synaptic depression induced by pharmacological activation of metabotropic glutamate receptors in the perirhinal cortex in vitro [PDF]

, 1999
The perirhinal cortex is crucially involved in various forms of learning and memory. Decrements in neuronal responsiveness occur in the perirhinal cortex with stimulus repetition during visual recognition performance.
Brown, M. W., Collingridge, G. L., K Cho, Z.A Bortolotto, J.P Aggleton, Cho, K., Z.I Bashir, M.W Brown, G.L Collingridge, F Conquet, Bortolotto, Z. A., B McCaffery, Conquet, F., Bashir, Z. I., McCaffery, B., Aggleton, John   +15 more
core   +1 more source

Reduced ictogenic potential of 4-aminopyridine in the perirhinal and entorhinal cortex of kainate-treated chronic epileptic rats

Neurobiology of Disease, 2008
We investigated the potential of 4-AP (50–100 μM) to induce seizure-like events (SLEs) in combined entorhinal cortex–hippocampal slices from Sprague Dawley rats which developed spontaneous limbic seizures following kainic acid induced status epilepticus.
Robert K. Zahn, Else A. Tolner, Christian Derst, Clemens Gruber, Rüdiger W. Veh, Uwe Heinemann   +5 more
doaj   +1 more source

Reduced CB1 Cannabinoid Receptor Expression in Alzheimer's Disease and Transgenic Mouse Models

AGING MEDICINE, Volume 9, Issue 2, Page 168-184, April 2026.
CB1 receptor (CB1R) expression was significantly reduced in the hippocampus, medial frontal gyrus, and superior temporal gyrus of Alzheimer's patients. CB1R levels negatively correlated with amyloid‐β and tau pathology. In addition, CB1R expression was also reduced in the cortex of 5xFAD mice and in the hippocampus of Tg4‐42 mice.
Nike von Borcke, Amrei Vivian Purwien, Annik Steiert, Henrike Hasecke, Yvonne Bouter   +4 more
wiley   +1 more source

A computational model of basal ganglia and its role in memory retrieval in rewarded visual memory tasks

Frontiers in Computational Neuroscience, 2010
Visual working memory tasks involve a network of cortical areas such as inferotemporal, medial temporal and prefrontal cortices. We suggest here to investigate the role of the basal ganglia in the learning of delayed rewarded tasks through the selective ...
Julien Vitay, Fred H Hamker, Fred H Hamker   +2 more
doaj   +1 more source

Altered Brain Structure in an ATRX‐Deficient Mouse Model of Autism Spectrum Disorder

Autism Research, Volume 19, Issue 4, April 2026.
ABSTRACT Mutations in the ATRX gene are a primary cause of alpha‐thalassemia intellectual disability X‐linked (ATRX) syndrome, which is characterized by intellectual disability, autism, and a range of brain structural abnormalities, including microcephaly.
Katherine Quesnel, Jacob Ellegood, Jason P. Lerch, Nathalie G. Bérubé   +3 more
wiley   +1 more source

The role of perirhinal cortex in visual discrimination learning for visual secondary reinforcement in rats [PDF]

, 2003
Perirhinal cortex in monkeys has been thought to be involved in visual associative learning. The authors examined rats' ability to make associations between visual stimuli in a visual secondary reinforcement task.
Eacott, M.J., G. Norman, Gaffan, E.A., Norman, G., E. A. Gaffan, M. J. Eacott   +5 more
core   +1 more source

The Role of Dopamine Signaling and Neuroinflammation in Age‐Related Cognitive Dysfunction

Brain and Behavior, Volume 16, Issue 4, April 2026.
We reveal early disruption in synaptic integrity (PSD‐95, synaptophysin, BDNF), increased dopamine clearance (Comt, Net), and inflammatory signaling (Nfkb, Socs3) in the PFC, while the hippocampus remains largely resistant. These molecular “warning signs” precede behavioral deficits, highlighting potential targets for early intervention to protect ...
Junior Bowen, Katie Hanna, Andrew M. J. Young, Gisela Helfer, Samantha L. McLean   +4 more
wiley   +1 more source

The role of the human entorhinal cortex in a representational account of memory

Frontiers in Human Neuroscience, 2015
Connectivity studies in animals form the basis for a representational view of medial temporal lobe (MTL) subregions. In this view, distinct subfields of the entorhinal cortex (EC) relay object-related and spatial information from the perirhinal and ...
Heidrun eSchultz, Heidrun eSchultz, Tobias eSommer, Jan ePeters   +3 more
doaj   +1 more source