Results 101 to 110 of about 43,857 (235)

CHARGE Syndrome: A Narrative Review and Update on Diagnosis, Assessment and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background CHARGE syndrome (CS) is a rare multisystemic genetic condition caused by a pathogenic variant in the DNA‐binding protein‐7 CHD7 gene. The condition affects the development of neural crest cells, which give rise to craniofacial structures, cranial nerves, ears, eyes and the heart, resulting in diverse and complex clinical features ...
Eleni M. van Gelder, Suzanna E. L. Temple, Niall Jefferson, David Brown, Kasee Stratton‐Gadke, Madelene Rich, Steve Rose, Kim Blake   +7 more
wiley   +1 more source

Beyond Immunity: Functional Outcomes of Dietary Yeast and Seaweed β‐Glucans in Adult Canine Nutrition

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT β‐Glucans are functional compounds associated with health benefits; however, the physiological effects of different β‐glucan sources in dog foods remain incompletely understood. This study evaluated and compared the effects of β‐glucans derived from Euglena gracilis (seaweed) and Saccharomyces cerevisiae (yeast) on nutrient digestibility ...
Stephanie de Souza Theodoro, Maria Eduarda Gonçalves Tozato, Letícia Warde Luis, Camila Goloni, Jhennifer de Castro Fenerick, Lucas Bassi Scarpim, Isabel Ten Caten Bento, Connie Abril Rojas, Marcelino Bortolo, Aulus Cavalieri Carciofi   +9 more
wiley   +1 more source

Pharmacokinetics of a Single Subcutaneous Extended‐Release Buprenorphine (Ethiqa XR) in Healthy Beagles

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This study evaluated the pharmacokinetics of an extended‐release buprenorphine formulation (Ethiqa XR) in dogs and explored potential sex differences. Twelve healthy intact beagles (6 males and 6 females) received a single subcutaneous injection of Ethiqa XR (0.2 mg/kg).
Kornelia Tiffinger, Hiroko Enomoto, Ronald E. Baynes, Laura M. Neumann, B. Duncan X. Lascelles, Masataka Enomoto   +5 more
wiley   +1 more source

Clinical Significance of the Mean Nocturnal Baseline Impedance and Post-Reflux Swallow-Induced Peristaltic Wave Index in the Diagnosis of Gastroesophageal Reflux Disease

The Korean Journal of Gastroenterology
Gastroesophageal reflux disease (GERD) is a common condition characterized by the reflux of gastric contents into the esophagus, often leading to troublesome symptoms or complications.
Ju Yup Lee
doaj   +1 more source

Reflex Syncope With Complete Heart Block Triggered by Swallowing in a Patient on Immune Checkpoint Inhibitor Therapy

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) are now standard of care for most advanced solid tumors. While effective, they are associated with immune‐related adverse events (irAEs), including rare autonomic complications. We present a patient with metastatic lung adenocarcinoma receiving nivolumab and ipilimumab who developed reflex syncope with ...
Ashley Bouzon, Michael Oropesa, Bardia Adibmoradi, Daniel Weitz   +3 more
wiley   +1 more source

Modeling and analysis of electrokinetic actuation in peristaltic driving of Walter’s B fluid flow in symmetric conduits

Kuwait Journal of Science
This research examines the influence of electrokinetics on the peristaltic motion of a viscoelastic fluid confined inside a homogeneous geometric microstructure.
Xinwang Liu, S. Noreen, K. Rafique, U. Farooq, A.J. Chamkha   +4 more
doaj   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Efficiency and Safety of Endoscopic Injection Sclerotherapy With Ligation for Esophageal Varices: A Retrospective Study.

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Endoscopic injection sclerotherapy with ligation (EISL) is a combined endoscopic treatment that involves endoscopic injection sclerotherapy (EIS) and endoscopic variceal ligation. This study aimed to compare the efficacy of conventional EIS and EISL in treating esophageal varices and the usefulness of EISL.
Keita Maki, Hiroaki Haga, Kyoko Hoshikawa, Tomohiro Katsumi, Fumiya Suzuki, Fumi Uchiyama, Yoshiyuki Ueno   +6 more
wiley   +1 more source

Modification of the Biorelevant Release Testing of Esophageal Applied Mucoadhesive Films and Development of Formulation Strategies to Increase the Mucosal Contact Time

Pharmaceutics
The increasing prevalence of esophageal disease highlights the clinical relevance of novel, long-lasting mucoadhesive oral dosage forms. The EsoCap device enables targeted local application of films in the esophagus.
Friederike Brokmann, Paul Simonek, Christoph Rosenbaum   +2 more
doaj   +1 more source