Results 131 to 140 of about 43,857 (235)

The 9th International RASopathies Symposium

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1934-1941, August 2026.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel   +41 more
wiley   +1 more source

Chemical Profiles, Pharmacological Insights, and In Silico Studies of Antidesma montanum Blume: An Experimental and Computer‐Aided Approach

open access: yeseFood, Volume 7, Issue 4, August 2026.
Antidesma montanum, an edible wild plant, shows notable nutraceutical and pharmacological potential. Methanol extract profiling (GC–MS) identified bioactive metabolites. In vitro, in vivo, and in silico studies demonstrated significant antidiabetic, anthelmintic, anxiolytic, antidepressant, and antidiarrheal activities, supported by strong molecular ...
Naureen Banu   +9 more
wiley   +1 more source

Effects of Araticum (Annona crassiflora Mart.) By‐Product on Intestinal Health Parameters in High‐Fat Diet‐Fed Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Araticum (Annona crassiflora Mart.) by‐product supplementation at 200 or 400 mg/kg for 30 days did not improve body weight, glucose tolerance, or obesity‐related metabolic markers in high‐fat diet‐fed mice. However, it increased fecal moisture and intestinal mucus, reduced fecal pH, and promoted changes in gut bacterial richness, indicating potential ...
Thamara Rosa de Souza   +9 more
wiley   +1 more source

Efficacy and Tolerability of Tegoprazan Compared to Proton Pump Inhibitors in the Treatment of Erosive Esophagitis: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesJGH Open, Volume 10, Issue 8, August 2026.
ABSTRACT Aim Tegoprazan, a potassium‐competitive acid blocker, is an acid‐suppressing medication under review as a potential alternative treatment in cases of erosive esophagitis. This systematic review and meta‐analysis assesses the efficacy and tolerability of tegoprazan compared to proton pump inhibitors, the current standard of care. Methods Pubmed,
Youssef Diab   +6 more
wiley   +1 more source

European Society for Paediatric Gastroenterology, Hepatology and Nutrition/North American Society for Pediatric Gastroenterology, Hepatology and Nutrition guidelines for treatment of functional constipation in children aged 0–18 years

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 2, Page 335-366, August 2026.
Abstract Objectives Functional constipation (FC) is common in childhood, significantly impacting quality of life. Since the 2014 international guideline, new evidence has been published, and methods on making guidelines have developed. This treatment guideline for FC in children aged 0–18 years is a collaborative effort of the European and North ...
Morris Gordon   +17 more
wiley   +1 more source

High Methoxyl Pectin Consistently Reduces β‐Carotene Bioaccessibility Across Various Gastrointestinal Digestion Conditions

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.
High methoxyl pectin (HMP) significantly reduced β‐carotene bioaccessibility in vitro. This was observed at various enzyme/bile concentrations and shear forces. ABSTRACT Dietary fiber could inhibit β‐carotene bioaccessibility by restricting its release from the food matrix, interfering with digestive enzyme activities, binding bile salts, or modifying ...
Anushka Shukla   +4 more
wiley   +1 more source

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