Results 111 to 120 of about 29,681 (254)

[Peritoneal adhesions: pathophysiology].

Il Giornale di chirurgia, 2008
Peritoneal adhesions will form as a consequence of all types of trauma of the peritoneal serosa, be they mechanical, thermal, chemical, infective, or ischemic. Any stimulation induces deposition on the serosa of a fibrin-rich exudate that results in a weaker or stronger adhesion of the viscera to other viscera or to the wall parietal peritoneum.
G, Fabiano, A, Pezzolla, R, Maiorino, F, Ferrarese   +3 more
openaire   +1 more source

Laparoscopic Methylene Blue Photodynamic Therapy for Intraabdominal Infection: A Preclinical Feasibility Study in a Rabbit Model of Perforated Appendicitis

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran, Korry T. Wirth, Matthew M. Byrne, Benjamin Gertsen, Eric Y. Wang, Darrian S. Hawryluk, Martin S. Pavelka, Nicole A. Wilson   +7 more
wiley   +1 more source

Evaluation of the Efficacy of Photobiomodulation Therapy, Therapeutic Ultrasound, and Boric Acid in the Prevention of Intra‐Abdominal Adhesions in an Experimental Rat Model: A Macroscopic, Histopathological, and Gene Expression Analysis

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives This study aimed to evaluate the efficacy of photobiomodulation therapy (PBMT), therapeutic ultrasound (TUS), boric acid (BA), and their combinations in preventing experimentally induced intra‐abdominal adhesions in rats. Materials and Methods Ninety‐six male Wistar rats (14 weeks old) were randomly assigned to eight groups (Control,
Sıtkıcan Okur, Büşra Baykal, Latif Emrah Yanmaz, Ayşe Gölgeli Bedir, Damla Tuğçe Okur, Mümin Gökhan Şenocak, Ferda Turgut, Serkan Yildirim, İsmail Bolat, Betül Apaydin Yildirim, Özlem Özdemir Tozlu   +10 more
wiley   +1 more source

Comparison of seprafilm and pitavastatin treatments in an experimental model of peritoneal adhesion

Scientific Reports
Peritoneal adhesions are common following abdominal surgery and lead to significant morbidity. Both pharmacological agents and barrier methods have been investigated for prevention, but with limited success. In this study, the efficacy of intraperitoneal
Hamza Çınar, Tuğrul Kesicioğlu, Utku Özgen, Arif Keskin, İsmail Aydın, Çağrı Akalın, Demet Şengül, Sevil Işık, Murat Usta   +8 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Independent Risk Factors for Postoperative Intestinal Obstruction and Clinical Outcomes in Simultaneous Pancreas‐Kidney Transplantation Recipients

Organ Medicine, EarlyView.
Intestinal obstruction (IO) is an important but underexplored complication following simultaneous pancreas‐kidney transplantation (SPKT) and is associated with considerable morbidity and both clinical and economic burdens. In this single‐center cohort study, perioperative parameters, including demographic characteristics, surgical variables, and ...
Rongxin Chen, Zebin Guo, Guanghui Li, Jiali Fang, Jialin Wu, Zhuangqiang Fang, Luhao Liu, Zheng Chen   +7 more
wiley   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

Injectable Zein‐Based Photothermal Composite Hydrogel Enhances Osteoporotic Tendon–Bone Healing

Small Methods, EarlyView.
Schematic illustration of the Zein‐based, dopamine‐grafted, niacin‐loaded carbon nanosphere (ZDC) composite hydrogel for enhancing healing of osteoporotic rotator cuff tears. This electron beam‐modified composite hydrogel is designed for NIR‐responsive release of niacin, which alleviates inflammation, promotes angiogenesis, and facilitates the ...
Kai Ye, Peng Ding, Zhenyou Dong, Wenyan Shi, Longxiang Shen, Xianyou Zheng   +5 more
wiley   +1 more source

Head‐to‐head prospective comparison of diagnostic accuracy of preoperative ultrasonography and MRI in patients undergoing surgery for deep endometriosis using #Enzian classification

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To perform a head‐to‐head comparison of the diagnostic performance of ultrasonography (US) vs magnetic resonance imaging (MRI) for the preoperative detection of endometriosis using the #Enzian classification system. Methods This was a prospective observational study of postmenarchal premenopausal women who underwent laparoscopy ...
B. Pete, K. Turtóczki, A. Bokor, I. Kalina, I. Madár, L. Lipták, J. Rigó Jr, N. Ács, G. Szabó   +8 more
wiley   +1 more source