Results 71 to 80 of about 42,197 (296)

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Plasma Levels of t-PA and PAI-1 Correlate With the Formation of Experimental Post-Surgical Peritoneal Adhesions

Mediators of Inflammation, 2006
This study has evaluated whether systemic changes of plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) parallel the adhesions development and whether they could be used as predictors of adhesion risk.
Clara Di Filippo, Alessandro Falsetto, Vito De Pascale, Elisabetta Tufariello, Domenico De Lucia, Francesco Rossi, Michele D'Amico, Antonio Cennamo   +7 more
doaj   +1 more source

Estudo da formação de aderências e da cicatrização de anastomoses colônicas em ratos com sepse peritoneal induzida [PDF]

, 2011
OBJETIVO: Avaliar os efeitos da sepse abdominal sobre a formação de aderências e a cicatrização de anastomoses colônicas em ratos. MÉTODOS: 40 ratos distribuídos em dois grupos contendo 20 animais, para anastomose do cólon esquerdo na presença (grupo S ...
Agalar F, Ahrendt GM, Alexandre Malta Brandão, Aydin C, Bedirli A, Biondo-Simões M LP, Biondo-Simões MLP, Biondo-Simões MLP, Bothin C, Buchs NC, Cahill RA, De Hann BB, De Hingh IH, Fabiana Pirani Carneiro, João Batista de Sousa, Liakakos T, Marcos Vinícius Melo de Oliveira, Nair SK, Naresse LE, Omar Feres, Ozen IO, Rittirsch D, Rocha AA, Rogério Serafim Parra, Silvana Marques e Silva, Teke Z, Vânia Maria Moraes Ferreira, Wang P   +27 more
core   +4 more sources

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Morphology of the canine omentum, part 2: the omental bursa and its compartments materialized and explored by a novel technique [PDF]

, 2016
The canine omental bursa is a virtual cavity enclosed by the greater and lesser omentum. While previous representations of this bursa were always purely schematic, a novel casting technique was developed to depict the three-dimensional organization of ...
Ackerknecht, Adams, Barone, Barone, Bergen, Budras, Casteleyn, Cornillie, De Sordi, Dux, Dux, Evans, Habel, Krucker, König, Meyer, Owaki, Rivero, Ryan, Viggiano, Zietzschmann   +20 more
core   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Neutrophil Extracellular Traps: A Crucial Factor in Post-Surgical Abdominal Adhesion Formation

Cells
Post-surgical abdominal adhesions, although poorly understood, are highly prevalent. The molecular processes underlying their formation remain elusive.
Yuqing Lu, Julia Elrod, Martin Herrmann, Jasmin Knopf, Michael Boettcher   +4 more
doaj   +1 more source

Hyperbaric oxygenation on adhesions prevention after laparotomy in rats [PDF]

Acta Cirúrgica Brasileira, 2018
Purpose: To evaluate the effects of hyperbaric oxygenation on prevention of adhesions in the abdominal cavity after laparotomy. Methods: Fifty four rats underwent laparotomy; stitches were made in the four quadrant parietal peritoneum and abdominal ...
Simone Vargas Bento, Tarcizo Afonso Nunes, Ivana Durval Araújo, Roberto Carlos Oliveira e Silva, Paula Vieira Teixeira Vidigal, Ricardo Machado Carvalhais   +5 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Vascular pattern of peritoneal adhesions

Journal of British Surgery, 1968
The number of blood tissues in adhesions caused by peritoneal injuries was studied for the purpose of testing the anoxia theory of adhesion formation. Experiments were performed on albino male rats. The experimental operative procedure involved multiple trauma of the peritoneum.
H, Myllärniemi, V, Karppinen
openaire   +2 more sources