Intraperitoneal metastasis of ovarian cancer: new insights on resident macrophages in the peritoneal cavity [PDF]
Frontiers in Immunology, 2023 Ovarian cancer metastasis occurs primarily in the peritoneal cavity. Orchestration of cancer cells with various cell types, particularly macrophages, in the peritoneal cavity creates a metastasis-favorable environment.
Taito Miyamoto +2 more
doaj +3 more sources
Activated peritoneal cavity B-1a cells possess regulatory B cell properties. [PDF]
PLoS ONE, 2014 Previous studies have suggested that murine peritoneal cavity-derived B-1a cells possess similarities with described regulatory B cell subsets. The aim of the current study was to examine the potential immunoregulatory function of peritoneal cavity ...
Bram Margry +6 more
doaj +13 more sources
The Host Peritoneal Cavity Harbors Prominent Memory Th2 and Early Recall Responses to an Intestinal Nematode [PDF]
Frontiers in Immunology, 2022 Intestinal parasitic nematodes affect a quarter of the world’s population, typically eliciting prominent effector Th2-driven host immune responses. As not all infected hosts develop protection against reinfection, our current understanding of nematode ...
Ivet A. Yordanova +7 more
doaj +3 more sources
GATA6+ Peritoneal Resident Macrophage: The Immune Custodian in the Peritoneal Cavity [PDF]
Frontiers in Pharmacology, 2022 Peritoneal resident macrophages (PRMs) have been a prominent topic in the research field of immunology due to their critical roles in immune surveillance in the peritoneal cavity. PRMs initially develop from embryonic progenitor cells and are replenished
Preethi Jayakumar +3 more
doaj +3 more sources
Directly recruited GATA6 + peritoneal cavity macrophages contribute to the repair of intestinal serosal injury. [PDF]
Nat Commun, 2021 Recruitment of bone marrow derived monocytes via bloodstream and their subsequent conversion to CX3CR1+ macrophages in response to intestinal injury is dependent on CCR2, Nr4a1, and the microbiome.
Honda M +4 more
europepmc +2 more sources
Specialized immune responses in the peritoneal cavity and omentum. [PDF]
J Leukoc Biol, 2021 The peritoneal cavity is a fluid filled space that holds most of the abdominal organs, including the omentum, a visceral adipose tissue that contains milky spots or clusters of leukocytes that are organized similar to those in conventional lymphoid ...
Liu M +3 more
europepmc +2 more sources
Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity [PDF]
Journal of Experimental Medicine, 2019 Macrophages resident in different organs express distinct genes, but understanding how this diversity fits into tissue-specific features is limited. Here, we show that selective expression of coagulation factor V (FV) by resident peritoneal macrophages ...
Broze, George J +12 more
core +3 more sources
Mouse Tissue‐Resident Peritoneal Macrophages in Homeostasis, Repair, Infection, and Tumor Metastasis
Advanced Science, 2023 Large peritoneal macrophages (LPMs) are long‐lived, tissue‐resident macrophages, formed during embryonic life, developmentally and functionally confined to the peritoneal cavity. LPMs provide the first line of defense against life‐threatening pathologies
Carlos Ardavín +4 more
doaj +2 more sources
Sporadic Neurofibroma of the Peritoneal Cavity. [PDF]
ACG Case Rep J, 2022 ABSTRACT Neurofibromas are peripheral nerve sheath tumors that are typically seen in syndromic conditions such as neurofibromatosis 1. We present the case of a 26-year-old woman suffering from chronic abdominal pain for over 5 years. Prior workup showed a large retroperitoneal mass extending into the abdomen and encasing multiple major ...
Shah RH +5 more
europepmc +3 more sources
The lectin ArtinM induces recruitment of rat mast cells from the bone marrow to the peritoneal cavity. [PDF]
PLoS ONE, 2010 BACKGROUND: The D-mannose binding lectin ArtinM is known to recruit neutrophils, to degranulate mast cells and may have potential therapeutic applications. However, the effect of ArtinM on mast cell recruitment has not been investigated.
Patricia Andressa de Almeida Buranello +5 more
doaj +2 more sources