Results 61 to 70 of about 114,294 (257)

Effect of sensor location on continuous intraperitoneal glucose sensing in an animal model. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:In diabetes research, the development of the artificial pancreas has been a major topic since continuous glucose monitoring became available in the early 2000's.
Marte Kierulf Åm   +9 more
doaj   +1 more source

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang   +8 more
wiley   +1 more source

Pelvic peritoneal reconstruction using the bladder peritoneum flap in a patient with radiation-induced small intestinal fistula

open access: yes结直肠肛门外科
Postoperative pelvic peritoneal defects and pelvic residual cavity after rectal cancer surgery are prone to cause related surgical complications, such as intestinal obstruction, hernia, and infection.
Xue Da   +4 more
doaj   +1 more source

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

open access: yesAdvanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen   +7 more
wiley   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

open access: yesAdvanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

open access: yesAdvanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang   +4 more
wiley   +1 more source

Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing

open access: yesCell & Bioscience, 2021
Background Endometriosis is a refractory and recurrent disease and it affects nearly 10% of reproductive-aged women and 40% of infertile patients. The commonly accepted theory for endometriosis is retrograde menstruation where endometrial tissues invade ...
Gen Zou   +9 more
doaj   +1 more source

Peritoneal Cavity Lymphatics [PDF]

open access: yesPeritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 1986
Lymphatic drainage of particulate matters from the peritoneal cavity occurs mainly from lacunae located in the diaphragm. These are a triple-layered structure consisting of mesothelium, a loose network of connective tissue and endothelium. Absorption of particles may occur via gap junctions, through the cells or via vesicles.
Ramesh Khanna   +3 more
openaire   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

open access: yesAdvanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral   +7 more
wiley   +1 more source

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