Results 61 to 70 of about 454,245 (301)

Imiquimod‐Loaded Phospholipid‐Free Small Unilamellar Vesicles Activate the Tumor Immune Microenvironment to Treat Liver Cancer and Liver Metastases

Advanced Healthcare Materials, EarlyView.
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan, Hsin‐Mei Lee, Haruka Takata, Sheng‐Liang Cheng, Yu‐Ting Yen, Lisa Pfeifer, Luke Rushton, Po‐Han Chao, Feng Zhao, Chun Yat Ong, Nojoud Al‐Fayez, Tatsuhiro Ishida, Yunching Chen, Shyh‐Dar Li   +13 more
wiley   +1 more source

Low-Protein Diet Supplemented with Keto Acids Is Associated with Suppression of Small-Solute Peritoneal Transport Rate in Peritoneal Dialysis Patients

International Journal of Nephrology, 2011
Objective. We investigate whether low-protein diet would show benefits in suppressing peritoneal transport rate in peritoneal dialysis (PD) patients. Methods.
Na Jiang, Jiaqi Qian, Aiwu Lin, Wei Fang, Weiming Zhang, Liou Cao, Qin Wang, Zhaohui Ni, Qiang Yao   +8 more
doaj   +1 more source

p-Cresyl sulfate [PDF]

, 2017
If chronic kidney disease (CKD) is associated with an impairment of kidney function, several uremic solutes are retained. Some of these exert toxic effects, which are called uremic toxins.
Glorieux, Griet, Gryp, Tessa, Vaneechoutte, Mario, Vanholder, Raymond   +3 more
core   +3 more sources

3D Bioprinted Renal Constructs Using Kidney‐Specific ECM Bioink System on Kidney Regeneration

Advanced Healthcare Materials, EarlyView.
A kidney‐specific bioink derived from decellularized porcine kidney tissue supports the encapsulation, viability, and maturation of human primary kidney cells within 3D bioprinted constructs. In vivo, it also promotes the recruitment of host renal progenitor cells, collectively enhancing structural and functional regeneration of renal tissue.
Gabriel Carreno‐Galeano, Mohamed Ali, James J. Yoo, Sang Jin Lee, Anthony Atala   +4 more
wiley   +1 more source

Effects of receiving renal biopsy on the prognosis of chronic kidney disease patients with impaired renal function

BMC Nephrology, 2023
Background Impaired renal function was not a recognized indication for renal biopsy. The effects of receiving renal biopsy on the renal functional prognosis for chronic kidney disease (CKD) patients with impaired renal function need to be explored ...
Tianyi Zhang, Xiaoqian Yang, Minfang Zhang, Wenyan Zhou, Yan Jin, Hang Zhou, Yin Zhou, Qin Wang, Shan Mou   +8 more
doaj   +1 more source

The future of European Nephrology 'Guidelines' - a declaration of intent by European Renal Best Practice (ERBP) [PDF]

, 2009
The disparities of medical practice, together with a growing number of possible interventions, have increased the demand for well-conceived guidance for practitioners [1].
Abramowicz, Daniel, Cannata-Andia, Jorge B., Cocchi, Valentina, Cochat, Pierre, Covic, Adrian, Eckardt, Kai-Uwe, Fouque, Denis, Heimburger, Olof, Jenkins, Simon, Lindley, Elisabeth, Locatelli, Francesco, London, Gérard, MacLeod, Alison, Marti i Monros, Ana, Spasovski, Goce, Tattersall, James, Van Biesen, Wim, Vanholder, Raymond, Wanner, Christoph, Wiecek, Andrej, Zoccali, Carmine   +20 more
core   +1 more source

eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR‐Mediated Metabolic Rewiring

Advanced Science, EarlyView.
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal, Minal Nenwani, Ishaque Pulikkal Kadamberi, Sudhir Kumar, Olamide Animasahun, Jasmine George, Shirng‐Wern Tsaih, Prachi Gupta, Mona Singh, Anjali Geethadevi, Chandrima Dey, Noah Meurs, Ajay Shankaran, Pradeep Chaluvally Raghavan, Deepak Nagrath, Sunila Pradeep   +15 more
wiley   +1 more source

Predicting Progression of Kidney Injury Based on Elastography Ultrasound and Radiomics Signatures

Diagnostics, 2022
Background: Shear wave elastography ultrasound (SWE) is an emerging non-invasive candidate for assessing kidney stiffness. However, its prognostic value regarding kidney injury is unclear.
Minyan Zhu, Lumin Tang, Wenqi Yang, Yao Xu, Xiajing Che, Yin Zhou, Xinghua Shao, Wenyan Zhou, Minfang Zhang, Guanghan Li, Min Zheng, Qin Wang, Hongli Li, Shan Mou   +13 more
doaj   +1 more source

Quality of life with conservative care compared with assisted peritoneal dialysis and haemodialysis [PDF]

, 2018
Background. There is little information about quality of life (QoL) for patients with end-stage kidney disease (ESKD) choosing conservative kidney management (CKM).
Barendse, Brown, Chandna, Da Silva-Gane, Davies, De Biase, Devins, Helvik, Hussain, Iyasere, Jakobsson, Jassal, Johansen, Kamar, Mahoney, Morton, Murphy, Murtagh, O'Connor, Okamoto, Rockwood, Roshanravan, Seow, Sexton, Shum, Verberne, Zigmond   +26 more
core   +4 more sources

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

Animal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera, Abeer Abdullah Alghamdi, Mesfer Al‐Shahrani, Reem M. Al‐Gahtani, Bashayer Saad Alghamdi, Gaffar Sarwar Zaman, Mohammed Abdul Rasheed, Hassan Al‐Shehri, Lana Al‐qhtani, Syed Parween Ali, Umme Hani, Talha Bin Emran   +11 more
wiley   +1 more source