Inhibition of STAT3 by S3I-201 suppress peritoneal fibroblast phenotype conversion and alleviate peritoneal fibrosis. [PDF]
Song Q +9 more
europepmc +1 more source
The Kampo Medicine Daikenchuto Inhibits Peritoneal Fibrosis in Mice
Mineaki Kitamura +8 more
openalex +1 more source
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic +2 more
wiley +1 more source
Astragalus membranaceus and its monomers treat peritoneal fibrosis and related muscle atrophy through the AR/TGF-β1 pathway. [PDF]
Sheng L +9 more
europepmc +1 more source
How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection
ABSTRACT Urinary tract infections possess substantial sex disparities in the incidence, immune response, and progression of infection. Some of these distinctions may be due to sexual dimorphism in mucosal barriers or sex differences in the initial immune response to infection.
Laura Ramirez Finn, Molly A. Ingersoll
wiley +1 more source
ABSTRACT Objective To explore the association between serum fibrinogen (FIB) and clinicopathological features and renal prognosis in type 2 diabetic nephropathy (T2DN), and develop a web‐based dynamic model to predict renal progression. Methods This paper retrospectively enrolled 173 biopsy‐proven T2DN patients and stratified them by the optimal FIB ...
Lin Ning +5 more
wiley +1 more source
Integrative analysis of chromatin accessibility and transcriptome landscapes in the induction of peritoneal fibrosis by high glucose. [PDF]
Song Q +8 more
europepmc +1 more source
Incisional Hernia Development: Wound Healing Gone Wrong?
ABSTRACT Incisional hernia (IH) is a common complication of abdominal surgeries, characterised by the protrusion of abdominal contents through a weakened surgical scar. Despite advancements in surgical techniques and biomaterials, IH remains a significant clinical and economic burden, with recurrence rates reaching up to 32% after repair.
Asim A. Abbas +3 more
wiley +1 more source
Dendritic Cell–Associated MARCKSL1 Regulates Fibroblast Differentiation During Wound Healing
ABSTRACT Following tissue injury, diverse cell populations, including immune cells such as dendritic cells, converge at the damaged site. They actively contribute to scar formation through intricate crosstalk with fibroblasts, exceeding their role as antigen‐presenting entities. Consequently, they are emerging as promising therapeutic targets.
Kento Takaya +6 more
wiley +1 more source

