Results 11 to 20 of about 18,535 (124)
Use of urethral catheters for diagnostic peritoneal lavage in blunt abdominal trauma [PDF]
, 2016 Background: Diagnostic peritoneal lavage (DPL) has been reported to be a reliable diagnostic tool in assessing the need for liparotomy in blunt abdominal trauma (BAT) with a diagnostic accuracy of more thin 95% when using a peritoneal lavage catheter ...
Kawooya, GM +3 more
core +2 more sources
The atypical chemokine receptor ACKR2 is protective against sepsis [PDF]
, 2018 Sepsis is a systemic inflammatory response as a result of uncontrolled infections. Neutrophils are the first cells to reach the primary sites of infection and chemokines play a key role in recruiting neutrophils.
Alves-Filho, José Carlos +15 more
core +1 more source
Peritoneal lavage in faecal peritonitis in the rat
Journal of British Surgery, 1978 Abstract Intraoperative antibiotic peritoneal lavage was significantly better than systemic antibiotic in preventing death from induced faecal peritonitis in the rat. Its efficacy was due to the combined effects of lavage and intraperitoneal antibiotic, each factor alone being significantly inferior to the combined effect of both ...
N. A. Matheson, D. J. Stewart
openaire +3 more sources
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing [PDF]
, 2007 Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but limited bacterial killing by these cells.
Clarke, Thomas B. +6 more
core +3 more sources
Advanced Science, EarlyView.Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui +17 more
wiley +1 more source
Advanced Science, EarlyView.This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua +19 more
wiley +1 more source
Diagnostic Peritoneal Lavage : an obituary? [PDF]
, 2006 Diagnostic peritoneal lavage (DPL) has been used as a diagnostic procedure in patients with blunt abdominal trauma for almost a century. Its accuracy and reliability are high.
Cassar, Kevin
core
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
Advanced Science, EarlyView.This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu +9 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.We retrospectively compared intracorporeal and extracorporeal anastomosis in patients undergoing laparoscopic colectomy for colon cancer in 46 institutions by using propensity‐score matching. Intracorporeal anastomosis showed advantages over extracorporeal anastomosis in terms of blood loss, intraoperative vascular injury, bowel recovery, and length of
Tomohiro Yamaguchi +92 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.The effectiveness of intraperitoneal chemotherapy using paclitaxel (i.p.‐PTX) in pancreatic ductal adenocarcinoma (PDAC) patients with peritoneal dissemination remains elusive. This study indicated that the i.p.‐PTX therapy may improve survival in selected patients with PDAC, in particular those with occult peritoneal dissemination.
Tomohisa Yamamoto +33 more
wiley +1 more source