Results 61 to 70 of about 17,743 (275)

Synthetic lethality in cancer therapy: Mechanisms, models and clinical translation for overcoming therapeutic resistance

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Application of synthetic lethality screening in drug resistance models. Abstract Background and Rationale Synthetic lethality (SL)‐based strategies hold significant promise for overcoming therapeutic resistance, a critical bottleneck in cancer treatment where cancer cells evade anticancer therapies, leading to diminished efficacy or treatment failure ...
Junyan Li   +4 more
wiley   +1 more source

A case of abdominal sarcoidosis in a patient with acute myeloid leukemia. [PDF]

open access: yes, 2013
The allogeneic bone marrow transplantation usually preceded by induction chemotherapy, in fit patients, represents the gold standard in the acute myeloid leukaemia.
Addeo, Alfredo   +4 more
core   +2 more sources

The Role of Macrophages in Cancer: From Basic Research to Clinical Applications

open access: yesMedComm, Volume 7, Issue 1, January 2026.
Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu   +5 more
wiley   +1 more source

Sarcomatoid malignant peritoneal mesothelioma: A rare case of sarcomatoid component with monosomy 9 appeared in ascites fluid

open access: yesHuman Pathology: Case Reports, 2019
Sarcomatoid mesothelioma (SM) is the rarest subtype of malignant mesothelioma (MM) with the poorest prognosis. Due to its aggressive nature, early diagnosis and treatment are required for SM, resulting in they significantly improve patient survival ...
Yuri Noda   +3 more
doaj   +1 more source

Pediatric Peritoneal Epithelial Malignant Mesothelioma Case Report

open access: yesCase Reports in Radiology, 2021
We present a 14-year-old boy with peritoneal epithelial malignant mesothelioma (PEMM). While pathology is required to make this diagnosis, radiology plays a crucial role throughout the clinical course of this disease.
Elizabeth Bellew   +5 more
doaj   +1 more source

Effusion‐Dominant Pulmonary Sarcomatoid Carcinoma Without a Primary Mass: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
We describe a patient with high‐grade sarcomatoid carcinoma presenting as malignant pleural effusion without a primary mass. This case highlights the diagnostic challenges, aggressive clinical course, and importance of early biopsy. We also review the limited literature describing similar presentations.
Sze Kye Teoh   +5 more
wiley   +1 more source

Recurrent malignant peritoneal mesothelioma treated by a second resection: A case report

open access: yesClinical Case Reports, 2023
Key Clinical Message Malignant peritoneal mesothelioma, a rare and poor prognosis disease, is seldom treated surgically, especially for recurrence. However, early diagnosis and aggressive treatment of primary and recurrent tumors can achieve long‐term ...
Takashi Miyata   +15 more
doaj   +1 more source

Mesothelioma response to carbon nanotubes is associated with an early and selective accumulation of immunosuppressive monocytic cells [PDF]

open access: yes, 2015
BACKGROUND: The asbestos-like toxicity of some engineered carbon nanotubes (CNT), notably their capacity to induce mesothelioma, is a serious cause of concern for public health.
Christian Bailly   +14 more
core   +3 more sources

Multicystic peritoneal mesothelioma.

open access: yesThe American journal of case reports, 2012
Multicystic peritoneal mesothelioma is a rare disease. It is not certain if it is a benign or a borderline tumor. Although many therapeutic approaches have been used, complete cytoreductive surgery in combination with hyperthermic intraoperative intraperitoneal chemotherapy has gained acceptance.A case of multicystic peritoneal mesothelioma in a 16 ...
Tentes, Antonios-Apostolos   +3 more
openaire   +2 more sources

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