Results 61 to 70 of about 260,154 (263)

Malignant peritoneal mesothelioma

Saudi Medical Journal, 2000
Malignant peritoneal mesotheliomas are rare tumors arising from the peritoneal surface. We report a 53 year old, non-asbestos exposed Saudi male who presented with exudative ascites. The diagnosis was obtained from laparoscopic biopsy. To the best of our knowledge this entity has not been described in the Saudi community.
S M, Al-Amri, R H, Rahmatulla, I A, Al-Bozom   +2 more
openaire   +2 more sources

BAP1 haploinsufficiency predicts a distinct immunogenic class of malignant peritoneal mesothelioma

Genome Medicine, 2019
Malignant peritoneal mesothelioma (PeM) is a rare and fatal cancer that originates from the peritoneal lining of the abdomen. Standard treatment of PeM is limited to cytoreductive surgery and/or chemotherapy, and no effective targeted therapies for PeM ...
Raunak Shrestha, Noushin Nabavi, Yen-Yi Lin, Fan Mo, Shawn Anderson, S. Volik, Hans Adomat, D. Lin, Hui Xue, Xin Dong, R. Shukin, Robert Bell, B. McConeghy, A. Haegert, Sonal Brahmbhatt, Estelle Li, H. Oo, A. Hurtado-coll, L. Fazli, Joshua Zhou, Y. McConnell, A. Mccart, A. Lowy, Gregg B. Morin, Tianhui Chen, M. Daugaard, S. C. Sahinalp, F. Hach, Stephane Le Bihan, M. Gleave, Yuzhu Wang, A. Churg, Colin C. Collins   +32 more
semanticscholar   +1 more source

The Diagnostic Value of Immunohistochemistry and Biomarkers in the Diagnosis of Mesothelioma in Pleural/Peritoneal Effusions

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Mesothelioma is a rare tumor that arises from the serosal cells lining the serous cavities, most commonly the pleura followed by the peritoneum. Presenting symptoms include pleuritic pain and bloody effusions that recur. Although cytologic analysis cannot determine the mesothelial subtype or in situ from invasive disease, the ...
Suzanne M. Selvaggi
wiley   +1 more source

Dramatic tumour response to pemetrexed single-agent in an elderly patient with malignant peritoneal mesothelioma: a case report

BMC Cancer, 2006
Background To date, there is no standard treatment for unresectable malignant peritoneal mesothelioma; either best supportive care or systemic chemotherapy with palliative intent are accepted options.
Di Terlizzi Silvia, Aita Marianna, Follador Alessandro, Puglisi Fabio, Fasola Gianpiero, Belvedere Ornella   +5 more
doaj   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

International Journal of Cancer, EarlyView.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley, Liesbet J. Van Eycken, Meredith E. Giuliani, Brian A. Rous, Shao Hui Huang, Hisao Asamura, Mary K. Gospodarowicz, Anne W. Lee, Brian O'Sullivan   +8 more
wiley   +1 more source

New Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives Inhibit FAK Phosphorylation and Potentiate the Antiproliferative Effects of Gemcitabine Through Modulation of the Human Equilibrative Nucleoside Transporter-1 in Peritoneal Mesothelioma

Anticancer Research, 2020
Background/Aim: A new class of imidazo[2,1-b][1,3,4]thiadiazole compounds have recently been evaluated as inhibitors of phosphorylation of focal adhesion kinase (FAK) in pancreatic cancer.
Giovanna Li Petri, Camilla Pecoraro, O. Randazzo, S. Zoppi, S. Cascioferro, B. Parrino, D. Carbone, B. El Hassouni, A. Cavazzoni, N. Zaffaroni, G. Cirrincione, P. Diana, G. Peters, E. Giovannetti   +13 more
semanticscholar   +1 more source

Case report: A1159T mutation in malignant peritoneal mesothelioma may be associated with tumor recurrence

SAGE Open Medical Case Reports
Malignant peritoneal mesothelioma is an exceedingly rare malignant tumor. Herein, we present a case of malignant peritoneal mesothelioma in a 59-year-old Chinese female patient who was stable after treatment for multiple relapses.
Ying Li, Jintao Yang, Bei Zheng, Na Yan, Wenjuan Yang, Xinling Xie, Guoshu Xu, Meiling Zhang   +7 more
doaj   +1 more source

Computed tomography findings of peritoneal tumour in the absence of primary lesions: preliminary study

Australian Veterinary Journal, EarlyView.
Primary peritoneal tumours are uncommon and include mesothelioma and carcinoma. Mesothelioma identification is challenging, as there are no established rapid diagnostic methods. In the absence of a simple means of diagnosis, evaluation often requires several invasive biopsies, highlighting the need to develop a definitive diagnostic method.
T Tanaka, M Tomihari, T Hasegawa
wiley   +1 more source

Mesothelioma location influences the tumour microenvironment and immune checkpoint therapy response in preclinical models

Scientific Reports
Mesothelioma is a cancer derived from mesothelial cells, most commonly arising from the pleura or the peritoneum. Immune checkpoint therapy (ICT) has shown survival benefit for pleural mesothelioma, but little is known about the response in peritoneal ...
M. Lizeth Orozco Morales, Sally M. Lansley, Wee Loong Chin, Caitlin M. Tilsed, Nicola Principe, Connull Leslie, Breana J. Vitali, Francois X. Rwandamuriye, Emma de Jong, Joel Kidman, Rachael M. Zemek, Catherine A. Rinaldi, Timo Lassmann, Anthony Bosco, Y. C. Gary Lee, Richard A. Lake, Jonathan Chee, W. Joost Lesterhuis   +17 more
doaj   +1 more source

Urokinase Plasminogen Activator Receptor‐Associated Protein (uPARAP) as a Potential Next Generation Molecular Target for Treatment of Gastrointestinal Stromal Tumors (GIST)

International Journal of Cancer, Volume 159, Issue 3, Page 797-808, 1 August 2026.
A key component of the collagen internalization and lysosomal degradation cellular machinery, uPARAP may contribute to cancer progression. Here, the authors explored the expression of uPARAP in gastrointestinal stromal tumors using well‐annotated clinical patient samples and specimens from cell line‐ and patient‐derived xenografts.
Chao‐Chi Wang, Flavia Paternostro, Agnieszka Wozniak, Lore De Cock, Luna De Sutter, Kimberly Verbeeck, Ulla Vanleeuw, Daniël Gorgels, Che‐Jui Lee, Raf Sciot, Patrick Schöffski   +10 more
wiley   +1 more source