Results 171 to 180 of about 59,311 (364)

Explainable machine learning for neoplasms diagnosis via electrocardiograms: an externally validated study [PDF]

open access: yesarXiv
Background: Neoplasms remains a leading cause of mortality worldwide, with timely diagnosis being crucial for improving patient outcomes. Current diagnostic methods are often invasive, costly, and inaccessible to many populations. Electrocardiogram (ECG) data, widely available and non-invasive, has the potential to serve as a tool for neoplasms ...
arxiv  

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

open access: yesAdvanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua   +19 more
wiley   +1 more source

Intestinal obstruction due to malign breast neoplasm and peritoneal carcinomatosis: a case report [PDF]

open access: diamond, 2012
Flávia Balsamo   +3 more
openalex   +1 more source

Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications

open access: yesAdvanced Science, EarlyView.
Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian   +5 more
wiley   +1 more source

Case report of peritoneal carcinomatosis in the clinical course of pancreatic solid pseudopapillary neoplasm (Frantz's tumor) in a patient with a history of blunt abdominal trauma

open access: gold, 2023
Sérgio Henrique Bastos Damous   +5 more
openalex   +1 more source

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

open access: yesAdvanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang   +13 more
wiley   +1 more source

Propuesta de enfoque diagnóstico y terapéutico de la carcinomatosis peritoneal originada en el colon

open access: yesRevista Colombiana de Cirugía
Introducción. El cáncer colorrectal corresponde a la cuarta causa de cáncer a nivel mundial, con una incidencia de 17,2 por cada 100.000 habitantes, y en Colombia es de 10,6 por 100.000, con gran mortalidad. El cáncer metastásico a peritoneo se considera
Mauricio García   +2 more
doaj  

The inhibitory effect of Yam polysaccharides on acrylamide‐induced programmed cell death in RAW 264.7 cells

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 443-457, January 2023., 2023
Acrylamide triggered macrophage cell apoptosis and autophagy and pyroptosis. ;P2X7 was of great significance in acrylamide‐induced cell death, but was mainly responsible for the regulation of autophagy and pyroptosis. Acrylamide stimulated oxidative stress via P2X7 in macrophage cells.
Jing Wang   +5 more
wiley   +1 more source

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