Results 121 to 130 of about 121,178 (316)

Localization Matters: Impacts of PEG‐J Localization in Intestinal Levodopa Therapy for Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Real‐world clinical evidence is missing to understand the resorption characteristics of levodopa through duodenal and jejunal parts of the small intestine. Objective To characterize how different application sites of intestinal levodopa gel would impact on levodopa dosing and clinical outcomes. Methods This multicentre retrospective
Philipp Klocke   +11 more
wiley   +1 more source

Deep Learning Segmentation of Ascites on Abdominal CT Scans for Automatic Volume Quantification [PDF]

open access: yes
Purpose: To evaluate the performance of an automated deep learning method in detecting ascites and subsequently quantifying its volume in patients with liver cirrhosis and ovarian cancer. Materials and Methods: This retrospective study included contrast-enhanced and non-contrast abdominal-pelvic CT scans of patients with cirrhotic ascites and ...
arxiv   +1 more source

Levodopa–Entacapone–Carbidopa Intrajejunal Infusion in Advanced Parkinson's Disease – Interim Analysis of the ELEGANCE Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Levodopa–entacapone–carbidopa intestinal gel (LECIG) was introduced in 2018 as a device‐aided therapy for advanced Parkinson's disease (PD). Objectives The ELEGANCE study (NCT05043103) is gathering real‐world data on long‐term efficacy, safety and patient‐reported outcomes with LECIG from 13 European countries.
Daniel Weiss   +10 more
wiley   +1 more source

Ileo‐rectal anastomosis in ulcerative colitis—Long‐term outcome, failure and risk of cancer at a tertiary centre

open access: yesColorectal Disease, Volume 24, Issue 12, Page 1535-1542, December 2022., 2022
Abstract Aim Ileo‐rectal anastomosis (IRA) is an option to restore bowel continuity after colectomy in patients with ulcerative colitis (UC). Concerns that the remaining rectum may serve as a site for continuing proctitis with subsequent poor function and IRA failure and the fear of development of dysplasia and cancer have led to the abandonment of IRA
John Berghog   +4 more
wiley   +1 more source

Distinct changes in the colonic microbiome associated with acute diverticulitis

open access: yesColorectal Disease, Volume 24, Issue 12, Page 1591-1601, December 2022., 2022
Abstract Aim The pathogenesis of acute diverticulitis (AD) remains incompletely understood, despite it being one of the most common gastrointestinal conditions worldwide. The aim of this study was to investigate the role of the colonic microbiome in the pathogenesis of AD.
O’Grady MJ   +4 more
wiley   +1 more source

Improved surgical outcomes following simultaneous pancreas‐kidney transplantation in the contemporary era

open access: yesClinical Transplantation, Volume 36, Issue 11, November 2022., 2022
Abstract Background Complications leading to early technical failure have been the Achilles’ heel of simultaneous pancreas‐kidney transplantation (SPKT). The study purpose was to analyze longitudinally our experience with early surgical complications following SPKT with an emphasis on changes in practice that improved outcomes in the most recent era ...
Berjesh Sharda   +9 more
wiley   +1 more source

Realtime Particulate Matter and Bacteria Analysis of Peritoneal Dialysis Fluid using Digital Inline Holography [PDF]

open access: yesarXiv
We developed a digital inline holography (DIH) system integrated with deep learning algorithms for real-time detection of particulate matter (PM) and bacterial contamination in peritoneal dialysis (PD) fluids. The system comprises a microfluidic sample delivery module and a DIH imaging module that captures holograms using a pulsed laser and a digital ...
arxiv  

Pharmacotherapy for Cirrhosis in Japan

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
As cirrhosis progresses from the compensated to the decompensated stage, liver disease‐related events such as varices, ascites, encephalopathy, sarcopenia, jaundice, and bleeding tendency, as well as liver carcinogenesis, can occur at a high rate. With the advent of new pharmacotherapies for cirrhosis in the last decade, liver fibrosis has been shown ...
Hiroki Nishikawa, Soo Ki Kim, Akira Asai
wiley   +1 more source

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