Results 161 to 170 of about 117,040 (263)

Molecular Quantification of Fibrogenesis and Macrophage Activation Associate With Clinical Worsening in Patients With Cirrhosis

open access: yesLiver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT Knowledge of the potential of biomarkers for monitoring clinical improvement, assessing trajectory or disease progression in advanced chronic liver disease is still insufficient. This study investigated biomarkers of fibrosis and macrophage activation over time in newly diagnosed patients with cirrhosis and their potential association with ...
Emilie Toft Skovgaard   +8 more
wiley   +1 more source

Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi   +3 more
wiley   +1 more source

Hepatic Arterial Infusion Chemotherapy plus either Toripalimab or Sorafenib as First‐line Therapy for Locally Advanced Hepatocellular Carcinoma: A Non‐comparative, Randomized Phase 2 Trial

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This phase II study explored the efficacy and safety of HAIC plus toripalimab in locally advanced HCC. The primary endpoint was the PFS rate at 6 months. The 6‐month PFS rate was 63.9% in the TorHAIC group and 61.1% in the SoraHAIC group. Treatment with the TorHAIC regimen resulted in a median OS of 20.9 months and a median PFS of 9.1 months.
Zhicheng Lai   +12 more
wiley   +1 more source

Aerobic Microbiological Profile and Antimicrobial Resistance Trends in Sterile Body Fluid Infections Over Nine Years: A Retrospective Analysis from a Tertiary-Care Center. [PDF]

open access: yesInfect Drug Resist
Alharbi NA   +12 more
europepmc   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang   +3 more
wiley   +1 more source

Epidemiological Profile, Clinical Presentations, and Complications of Gunshot Wounds in Patients Admitted to a Tertiary Hospital in the Armed Conflict Zone of Goma in Eastern DR Congo

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
Gunshot wounds in eastern Democratic Republic of Congo primarily affect young men, with limb injuries being the most common and complications associated with open fractures and abdominal trauma. Hemodynamic instability upon admission and a delay in treatment exceeding 8 h significantly increase the risk of complications, highlighting the need to ...
Samuel Mbabazi   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy