Results 31 to 40 of about 117,040 (263)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Peritoneal lavage in appendicular peritonitis

Journal of British Surgery, 1978
Abstract Peritoneal lavage resulted in a significant reduction in the duration of hospital stay in a retrospective series of 189 children with peritonitis secondary to perforation of the appendix. Antibiotic peritoneal lavage also resulted in a significant reduction in the number of children with septic and adhesive complications ...
D J, Stewart, N A, Matheson
openaire   +2 more sources

Annual Report of the 2022 National Clinical Database: Decade‐Long Trends and Current Status of Gastroenterological Surgery in Japan

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The National Clinical Database (NCD) of Japan is the largest nationwide registry, covering over 95% of surgeries in the country. This 2022 annual report summarizes the short‐term outcomes of gastroenterological surgeries and discusses trends and insights over the past decade.
Koshi Kumagai, Arata Takahashi, Hideki Ueno, Naoki Hiki, Yoshiki Kajiwara, Tomoki Ebata, Takao Otsuka, Taro Oshikiri, Yoshihiro Kakeji, Takanori Goi, Akio Saiura, Hiroshi Saeki, Chie Tanaka, Masanori Tokunaga, Tsutomu Fujii, Satoru Matsuda, Tsunekazu Mizushima, Hiroyuki Yamamoto, Yuko Kitagawa, Ken Shirabe   +19 more
wiley   +1 more source

An Unusual Cause of Peritonitis in a Peritoneal Dialysis Patient: Leifsonia aquatica

Turkish Journal of Nephrology, 2021
Peritonitis continues to be an important cause of catheter losses in peritoneal dialysis (PD) patients. Although the causes of peritonitis are predominantly Gram-positive bacteria, Gram-negative bacteria and Fungi also appear as causative agents ...
Nagihan Özkarabıyık, İlyas Öztürk, Ertuğrul Erken, Özkan Güngör, Orçun Altunören   +4 more
doaj   +1 more source

Reappraisal of Real‐World Management of Acute Cholecystitis in Elderly Patients Based on the Adherence to Tokyo Guidelines 2018 (TG18): A Multicenter Study on Anzu HPB Surgical Meeting

Annals of Gastroenterological Surgery, EarlyView.
This multicenter retrospective study analyzes real‐world management of acute cholecystitis in patients aged ≥ 70 years across five institutions, focusing on adherence and intentional deviation from TG18 recommendations. By classifying treatment strategies as TG18‐accordant, more aggressive, or more conservative, we reappraise current practice patterns.
Yuta Kobayashi, Shojiro Hata, Ryo Oikawa, Tetsuya Nakazato, Hiroki Sakata, Hirokazu Yamaguchi, Yutaka Suzuki, Yoshihiro Sakamoto   +7 more
wiley   +1 more source

Repeat peritonitis in peritoneal dialysis : A cohort study

Bulletin de la Dialyse à Domicile
Introduction: The understanding of the pathophysiological mechanisms of repeat peritonitis, defined as the occurrence of peritonitis more than 4 weeks after the end of appropriate antibiotic treatment for a previous episode involving the same germ ...
Nabil Hmaidouch, Sara El Maakoul, Hajar Fitah, Naima Ouzeddoun, Loubna Benamar   +4 more
doaj   +1 more source

Predictive value of the CT Scan in comparison with laparotomy in the diagnosis of peritonitis in COVID-19 patients [PDF]

Journal of Shahrekord University of Medical Sciences
Background and aims: The present study aimed to investigate the predictive value of the computed tomography (CT) scan in diagnosing peritonitis compared to laparotomy in COVID-19 patients. Methods: This study evaluated 11 COVID-19 patients with suspected
Naser Masoudi, Seifollah Rezaei, Nader Davoudi   +2 more
doaj   +1 more source

Prophylactic antibiotics for endoscopy-associated peritonitis in peritoneal dialysis patients. [PDF]

PLoS ONE, 2013
INTRODUCTION: Continuous ambulatory peritoneal dialysis (CAPD) peritonitis may develop after endoscopic procedures, and the benefit of prophylactic antibiotics is unclear.
Hsin-Hsu Wu, I-Jung Li, Cheng-Hao Weng, Cheng-Chia Lee, Yung-Chang Chen, Ming-Yang Chang, Ji-Tseng Fang, Cheng-Chieh Hung, Chih-Wei Yang, Ya-Chung Tian   +9 more
doaj   +1 more source

Emergency Cholecystectomy in Patients Classified as High Risk According to the Tokyo Guidelines 2018: A Real‐World Analysis

Annals of Gastroenterological Surgery, EarlyView.
Emergency cholecystectomy was evaluated in patients with acute cholecystitis classified as non‐recommended for surgery by the Tokyo Guidelines 2018. Major postoperative complications, rather than mortality, better reflected operative risk. Physiological instability, particularly ASA‐PS ≥ 3 and shock status, identified high‐risk patients, suggesting ...
Satoshi Mii, So Yamaki, Daisuke Hashimoto, Kazuki Matsumura, Hiroyuki Ishida, Hidetaka Miyazaki, Yuki Matsui, Yuji Ikeda, Tsukasa Ikeura, Sohei Satoi   +9 more
wiley   +1 more source