Perivascular Fat Attenuation Index by Computed Tomography as a Metric of Coronary Inflammation
We read with interest the study of Ohyama et al. [(1)][1] that linked vasospastic angina with perivascular adipose tissue (PVAT) volume and inflammation. The role of PVAT in vascular disease pathogenesis is currently well-accepted and supported by both translational and clinical evidence [(2,3 ...
Alexios S, Antonopoulos +1 more
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Thoracic fat volume is independently associated with coronary vasomotion. [PDF]
Thoracic fat has been associated with an increased risk of coronary artery disease (CAD). As endothelium-dependent vasoreactivity is a surrogate of cardiovascular events and is impaired early in atherosclerosis, we aimed at assessing the possible ...
Allenbach, G. +6 more
core +1 more source
Predictive value of the perivascular fat attenuation index and delta-CT-FFR for the formation of atherosclerotic plaques proximal to left anterior descending myocardial bridges. [PDF]
Feng D +7 more
europepmc +2 more sources
Accumulation of epicardial fat rather than visceral fat is an independent risk factor for left ventricular diastolic dysfunction in patients undergoing peritoneal dialysis [PDF]
BACKGROUND: Symptoms of heart failure with preserved left ventricular systolic function are common among patients undergoing peritoneal dialysis (PD).
Cho-Kai Wu +5 more
core +1 more source
Evaluation of pericoronary adipose tissue attenuation on CT [PDF]
Pericoronary adipose tissue (PCAT) is the fat deposit surrounding coronary arteries. Although PCAT is part of the larger epicardial adipose tissue (EAT) depot, it has different pathophysiological features and roles in the atherosclerosis process.
De Cecco, Carlo N. +6 more
core +4 more sources
Perivascular adipose tissue (PVAT) has been identified to have significant endocrine and paracrine functions, such as releasing bioactive adipokines, cytokines, and chemokines, rather than a non-physiological structural tissue. Considering the contiguity
Yan Liu +9 more
doaj +1 more source
Emerging cardiac CT biomarkers: a systematic review of diagnostic and prognostic utility in cardiovascular disease [PDF]
Background: Cardiac computed tomography (CT) has evolved from an anatomic test to a platform that quantifies functional, inflammatory, and tissue-characterization biomarkers.
Mubariz Ahmed Hassan +9 more
doaj +1 more source
Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data [PDF]
Background Coronary artery inflammation inhibits adipogenesis in adjacent perivascular fat. A novel imaging biomarker—the perivascular fat attenuation index (FAI)—captures coronary inflammation by mapping spatial changes of perivascular fat attenuation ...
Achenbach, S +20 more
core +2 more sources
Quantification of periaortic fat tissue in contrast-enhanced computed tomography [PDF]
Objective. Periaortic fat tissue (PaFT) has been implicated in the progression of abdominal aortic aneurysms (AAAs). Therefore, its quantification as a prognostic marker for aneurysm expansion has attracted clinical interest.
Mamopoulos, Apostolos
core +1 more source
Coronary computed tomography angiography (CTA) is a first-line investigation in suspected coronary artery disease ([1][1],[2][2]). Further to the detection of luminal stenosis, coronary CTA can characterize distinct high-risk plaque (HRP) features associated with an increased risk of adverse ...
Evangelos K, Oikonomou +9 more
openaire +2 more sources

