Results 101 to 110 of about 112,053 (349)

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Clinical Evaluation of a Self-Adhering Flowable Resin Composite in Minimally Invasive Class I Cavities: 5-year Results of a Double Blind Randomized, Controlled Clinical Trial

Acta Stomatologica Croatica, 2020
Objective: The aim of this study was to evaluate the long-term clinical performance of a self-adhering flowable resin composite compared to a conventional flowable resin composite used with an etch&rinse adhesive system in minimally invasive Class I ...
Fatma Dilsad Oz, Esra Ergin, Filiz Yalcin Cakir, Sevil Gurgan   +3 more
doaj   +1 more source

A Method of Locating the Abutment Screw Access Channel with Cone-Beam Computed Tomography and a 3D-Printed Drilling Guide [PDF]

, 2018
In managing loose abutment screws, locating precisely the position of the screw access channel is difficult. This technique describes the use of cone-beam computed tomography (CBCT) and surgical guide planning software to locate the screw access channel ...
Asiri, Waleed Nasir, Cho, Seok-Hwan, Domagala, Agnieszka, Thompson, Geoffrey A.   +3 more
core   +1 more source

Minimally invasive orthodontics: elastodontic therapy in a growing patient affected by Dentinogenesis Imperfecta [PDF]

, 2017
AIM: The aim of the study was to report the use of an elastodontic therapy in a growing patient affected by Dentinogenesis Imperfecta, second class malocclusion, deep bite and lower arch crowding from the deciduous dentition to permanent one. CASE
IERARDO, GAETANO, LUZZI, Valeria, NARDACCI, GIULIANA, POLIMENI, Antonella, VOZZA, Iole   +4 more
core   +1 more source

Irisin‐Loaded Cerium‐Containing Mesoporous Bioactive Glass for Effective Immunomodulation and Odontogenesis of Dental Pulp Cells

Advanced Science, EarlyView.
The Irisin/Ce‐MBGNs delivery system can slowly release myokine Irisin for vital pulp therapy. Irisin/Ce‐MBGNs can enhance mitochondrial function and promote the differentiation of inflammatory macrophages toward M2‐Mφ, thereby regulating the immune response mechanism of inflamed dental pulp.
Mingxin Wang, Yuxin Yang, Jingyao Guo, Yan Chen, Xiaolin Lu, Guangdong Zhang, Yuli Wang, Minhui Yao, Yue Liu, Qian Ma   +9 more
wiley   +1 more source

Effect of the ceramic translucency on the long-term water sorption and solubility of resin cements

Brazilian Journal of Oral Sciences, 2020
Aim: The aim of this study was to evaluate the influence of the translucency of ceramic on water sorption and solubility of resin cements over time. Methods: Lithium disilicate ceramic slides (15x15x1 mm), A1 in color and with different translucencies ...
Ana Paula Menezes Vaz Queiroz, Mariana Menezes Vaz Queiroz, Saryta Argolo, Richard Mark Foxton, Paula Mathias, Andrea Nóbrega Cavalcanti   +5 more
doaj   +1 more source

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

Advanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen, Jianqiang Yang, David O. Popoola, Fan Yang, Yajie Liu, Dongsheng Wang, Zhaohui S. Qin, Zhengjia Chen, Nabil F. Saba, Zhuo G. Chen, Yamin Li, Yong Teng   +11 more
wiley   +1 more source

Knowledge, attitudes, and behavior concerning dental trauma among parents of children attending primary school [PDF]

, 2016
BACKGROUND: Traumatic dental injuries occur frequently in children and adolescents. The purpose of the present study is to examine the levels of knowledge and behaviors regarding dental trauma among parents of children attending primary schools in the ...
Caggiano, G., DE GIGLIO, O, Montagna, Mt, Napoli, Christian, Quaranta, A, Trerotoli, P, Vaccaro, S   +6 more
core   +1 more source

Gas Bubbles from Biodegradable Magnesium Implants Convey Mechanical Cues and Promote Immune Cell Stimulation

Advanced Science, Volume 12, Issue 28, July 24, 2025.
Bubbles in soft tissue are the unavoidable consequence of magnesium implant degradation in patients, yet their biological significance remains unclear. Using advanced imaging and spatial transcriptomics, this study reveals a pronounced inflammatory and mechanical response near bubbles, contrasting with pro‐regenerative events closer to the implant ...
Heithem Ben Amara, Jincy Philip, Omar Omar, Peter Thomsen   +3 more
wiley   +1 more source

The dental phenotype of primary dentition in SATB2-associated syndrome: a report of three cases and literature review

BMC Oral Health, 2022
Background SATB2-associated syndrome (SAS; OMIM: 612,313) is an autosomal dominant inherited multisystemic disorder caused by several variants of the SATB2 gene.
Xiaojing Li, Xiaowei Ye, Jimei Su
doaj   +1 more source