Results 211 to 220 of about 67,720 (304)

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation

Sensory Neuroscience, EarlyView.
ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera, Nicole Ramones, Isabella Moceri, Sanjoy K. Bhattacharya   +3 more
wiley   +1 more source

Aesthetic Treatment of Bilateral Peg-Shaped Lateral Incisor and Restoration of a Harmonious Smile: A Case Report. [PDF]

Case Rep Dent
Alshehri A.
europepmc   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

Small, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen, Luke van der Koog, Robin A.B. Elferink, Karim Rafie, Anika Nagelkerke, Reinoud Gosens, Henderik W. Frijlink, Wouter L.J. Hinrichs   +7 more
wiley   +1 more source

Advances in knowledge and practice benefiting the health and management of first permanent molars in children. [PDF]

Br Dent J
Taylor GD, Bulmer V.
europepmc   +1 more source

Food—Consistency/Texture—Specific Pharyngeal Dystonia: A Novel Form of Focal Task‐Specific Dystonia

Movement Disorders Clinical Practice, EarlyView.
Domenico A. Restivo, Daniele Bruschetta, Angelo Alito, Enrico Alfonsi, Rosario Marchese‐Ragona, Angelo Quartarone   +5 more
wiley   +1 more source

Augmented 3D Printing for Multiscale Microphysiological Systems

Small, EarlyView.
This review explores augmented 3D printing techniques combined with multiscale ancillary methods to overcome current limitations in fabricating complex microphysiological systems (MPS). It covers 3D printing and ancillary techniques, and highlights advancements in augmented MPS that surpass conventional systems, offering more physiologically relevant ...
Kyeong Seob Hwang, Jiyoung Song, Hyun Wook Kang, Jongbaeg Kim, Cheol Woo Ha, Nakwon Choi, Seokyoung Bang, Hong Nam Kim   +7 more
wiley   +1 more source

Comprehensive space management and treatment of a patient with an early traumatic missing maxillary central incisor: a case report. [PDF]

BMC Oral Health
Chen L, Ouyang Z, Yao F.
europepmc   +1 more source

Developments of Thermosensitive Hydrogel for Maxillofacial Bone Regeneration

Small Science, EarlyView.
Thermosensitive hydrogel with seed cells and growth factors presents a new method for bone regeneration, changing states with temperature and offering fluidity, injectability, and controlled drug release. This article reviews thermosensitive hydrogel's role in angiogenesis, neurogenesis, and osteogenesis in maxillofacial bone regeneration and discusses
Qinrou Zhang, Ying Wu, Jialiang Dai, Zihan Jia, Minjia Zhu, Xinyi Li, Le Xiao, Jingyi Li, Zixiang Dai, Yuxing Bai, Jibin Song, Ke Zhang   +11 more
wiley   +1 more source

Fiber-Optimized Restoration: A Novel Approach to Strengthening Endodontic Posts With Dentapreg®. [PDF]

Cureus
Bansal S, Patri G, Majee N, Chatterjee I, Immanuel G.   +4 more
europepmc   +1 more source