Results 51 to 60 of about 10,994,822 (334)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Changes in agricultural climate in South-Eastern England from 1892 to 2016 and differences in cereal and permanent grassland yield [PDF]

open access: yes, 2021
The long-term increasing trend of annual mean temperature is only one aspect of recent climate change. Other changes in climate, seen in within-year weather patterns relevant to crop production, have also occurred since the late-19th Century ...
Addy, John W. G.   +9 more
core   +1 more source

Age-specific associations with dental caries in HIV-infected, exposed but uninfected and HIV-unexposed uninfected children in Nigeria

open access: yesBMC Oral Health, 2022
Background HIV infection and its management confer a substantial health burden to affected individuals and have been associated with increased risk of oral and dental diseases.
Paul Akhigbe   +10 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Levelling the Playing Field: The Effects of Slovenia’s 2013 Labour Market Reform

open access: yesEconomic and Business Review, 2019
The paper examines the effects of the 2013 labour market reform in Slovenia which made permanent contracts less restrictive and fixed-term contracts more restrictive.
Matija Vodopivec
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Policy, Institutional Factors and Earnings Mobility [PDF]

open access: yes
This paper uses ECHP and OECD data for 14 EU countries to explore the role of labour market factors in explaining cross-national differences in the dynamic structure of earnings: in permanent inequality, transitory inequality and earnings mobility. Based
Sologon, Denisa Maria   +1 more
core   +2 more sources

Rotary Mtwo system versus manual K-file instruments: Efficacy in preparing primary and permanent molar root canals

open access: yesIndian Journal of Dental Research, 2011
Aim: To compare the cleaning ability and preparation time of rotary instruments (Mtwo) and conventional manual instruments (K-file) in preparing primary and permanent molar root canals.
Mohammad-Reza Azar, Maziar Mokhtare
doaj   +1 more source

Zooplankton functional complementarity between temporary and permanent environments

open access: yesActa Limnologica Brasiliensia, 2021
: Aims This study aims to evaluate the functional complementarity of the zooplankton community between temporary ponds and permanent lagoons. We hypothesize that temporary environments will be functionally more diverse than permanent environments and ...
Rayanne Barros Setubal   +1 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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