Results 81 to 90 of about 10,994,822 (334)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Black/white differences in wealth [PDF]
This article studies the extent to which the wide gap in the wealth holdings of whites and African Americans can be explained by differences in family income and demographic characteristics.Wealth ; Income ...
Joseph G. Altonji +2 more
core
口腔疾病防治, 2019 Objective To research the root and root canal morphology of maxillary second permanent molars in the Guangfu population of the Lingnan area. Methods A total of 1220 maxillary second permanent molars were collected from the 723 CBCT images of the ...
LI Qi, HUANG Shaohong
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A permanent campaign? Tweeting differences among members of Congress between campaign and routine periods [PDF]
, 2019 This article investigates whether the notion of a “permanent campaign” characterizes politicians’ Twitter use by analyzing 285,456 tweets by Members of Congress during and after the 2016 US elections.
Trilling, D., Vasko, V.
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Employment consequences of restrictive permanent contracts: Evidence from Spanish labor market reforms [PDF]
Temporary employment contracts allowing unrestricted dismissals were introduced in Spain in 1984 and quickly came to account for most new jobs. As a result, temporary employment increased from around 10% in the mid-eighties to more than 30% in the early ...
Virginia Hernanz +2 more
core
The use of permanent and temporary jobs across Spanish regions: Do unit labour cost differentials offer an explanation? [PDF]
We study the use of permanent and temporary contracts across Spanish regions during the period 1995-2001. First we show that there are significant differences among the regional rates of permanent employment and that these differences tend to persist ...
J. Ignacio García-Pérez +1 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source