Results 71 to 80 of about 1,462,104 (294)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The Establishment of a Permanent Fire Brigade in Peterhof

open access: yesВестник Северного (Арктического) федерального университета: Серия «Гуманитарные и социальные науки»
This article covers the history of the establishment of such an important organization for any town as a fire service. The author notes that it was initiated by the head of the local palace administration Ya.Ya.
Andrey A. Efimov
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

La clef de la formation professionnelle offerte en milieu scolaire /

open access: yes, 1990
"Cet avis a été adopté par le Conseil permanent de la jeunesse à sa 14e séance, le 24 mars 1990"Bibliogr.: p. 41-43Notes bibliogr.
Québec (Province). Conseil permanent de la jeunesse   +1 more
core   +1 more source

Reemerging Sudan Ebola Virus Disease in Uganda, 2011

open access: yesEmerging Infectious Diseases, 2012
Two large outbreaks of Ebola hemorrhagic fever occurred in Uganda in 2000 and 2007. In May 2011, we identified a single case of Sudan Ebola virus disease in Luwero District.
Trevor Shoemaker   +11 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The service permanent establishment as defined by OECD An alternative to soften the permanent establishment concept

open access: yes, 2012
Diese Arbeit beschäftigt sich mit der Entwicklung zur Dienstleistungsbetriebsstätte iSd OECD. Ausgehend vom innerstaatlichen Recht wird der Begriff der Betriebsstätte iSd BAO untersucht, um anschließend die Definition und Funktion des ...
Wiechenthaler, Kurt
core   +2 more sources

Trait-mediated insect colonization of newly established grassland strips in agricultural landscapes

open access: yesBasic and Applied Ecology
Restoring grasslands in agroecosystems through the establishment of grassland and flowering strips has been demonstrated to promote insects. However, the development of the functional composition of insect assemblages in newly established grassland ...
Maria Peer   +14 more
doaj   +1 more source

Silesians at the Department of Theology of the Krakow University in the 15th century

open access: yesFolia Historica Cracoviensia, 1996
The establishment of universities in Prague, Vienna and Krakow enabled the Silesians to participate to a greater extent in the university culture of late Middle Ages.
Mieczysław Markowski
doaj   +1 more source

The new permanent establishment

open access: yes, 2023
The PE is a century-old concept with a fundamental role in the international taxation system via the fair allocation of taxing rights over cross-border business profits within the source-residence principles equilibrium, as a vital threshold for source taxation. Throughout its existence, this pivotal element has relied on its founding principles, which
openaire   +1 more source

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