Results 101 to 110 of about 1,462,409 (293)
L'accessibilité : c'est de valeur! : contrer les obstacles aux études postsecondaires : avis /
, 2005 "Cet avis a été adopté par le Conseil permanent de la jeunesse le 8 juin 2005 lors de sa 131e séance officielle"--P. [3].Mediagraphie: p.
Lemieux, Georges, +3 more
core +1 more source
Permanent establishment dilemma in the digital economy [PDF]
, 2014 M.Com. (South African and International Taxation)The concept of permanent establishment (PE) is a fundamental concept in international tax law, as it establishes the right to tax business profits of non-resident entities in the country where business ...
Chaffey, Al-Marie
core +1 more source
Analysis work and prospects Permanent International Criminal Court [PDF]
Zbornik Radova: Pravni Fakultet u Novom Sadu, 2018 The idea of the establishment of a Permanent International Criminal Court reached its peak thanks to the Rome Statute. Balancing between the two legal systems was an attempt to introduce a compromise the introduction of formal as well as in the material ...
Ćujić Miodrag P.
doaj
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Contemporary Condition, Problems and Prospects for Final Felling in the Republic of Belarus [PDF]
Сибирский лесной журнал, 2014 Contemporary status of forest use in the Republic of Belarus is discussed. The analysis of illegal logging in recent decades has been done. Final felling projections to 2030–2040 years is shown.
V. F. Baginski
doaj
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source