Results 31 to 40 of about 65,628 (266)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Yuridika, 2017 Permanent establishment is an expansion of foreign corporations which cannot perform any legal act in Indonesia. For that reason, it cannot be created into a corporation. Foreign corporations providing online application or internet-based content perform
Ragil Prastyawan +2 more
doaj +1 more source
Permanent establishment in digital business
Studia Prawno-Ekonomiczne, 2022 Background: As to the taxation of a permanent establishment (PE), current tax solutions based on the physical presence of an enterprise in the territory of another country have been developed for traditional enterprises that do not pursue their business digitally, especially on the Internet.
Marcin Jamroży, Filip Majdowski
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Integration in European Defence: Some Legal Considerations
European Papers, 2017 (Series Information) European Papers - A Journal on Law and Integration, 2017 2(3), 887-903 | Article | (Table of Contents) I. Introduction. - II. Reasons for the inclusion of EDU provisions in the Lisbon Treaty and their rationale. - III.
Luigi Lonardo
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEASIBILITY OF INVESTMENTS IN CULTIVATION OF TOMATOES IN PROTECTED AREAS [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2013 The main purpose of this paper is to identify the amount of investments required for the establishment of greenhouses, which would ensure quality, productivity and competitiveness of the products concerned.
Andrei ZBANCĂ, Ghenadie NEGRITU
doaj
Virtual Permanent Establishment: An Approach to the Taxation of Electronic Commerce Transactions
Revista de Derecho Fiscal, 2016 This article approaches to permanent establishment, the rules, and the taxation of electronic commerce transactions as a new “practice” in different countries around the world.
Ángela Carolina Vaca Bohórquez
doaj +1 more source